Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8 Puritas >98.0% (GC) Lenvatinib Mesylate Factory intermedia

Description:

Nomen chemicum: Methyl 4-Amino-2-Methoxybenzoate

CAS: 27492-84-8

Puritas: >98.0% (GC)

Aspectus: Alba ad Off-White vel Crystal

Medium de Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com


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Descriptio:

Chemical Properties:

Nomen chemicum Methyl 4-Amino-2-Methoxybenzoate
Synonyma 4-Amino-2-Methoxybenzoicum Acidum Methyl Ester;Methyl 4-Amino-o-Anisate;4-Amino-o-Anisic Acidum Methyl Ester
CAS Number 27492-84-8
CATTUS Number RF-PI1974
Stock Status In Stock, Productio Ascendite ad Tons
Formulae hypotheticae C9H11NO3
M. Pondus 181.19
Density 1.179±0.060 g/cm3
Brand Ruifu Chemical

Specifications:

Item Specifications
Aspectus Alba ad Off-White vel Crystal
Puritas / Analysis Methodus >98.0% (GC)
Puritas / Analysis Methodus 97.5~102.5
Liquescens punctum 157.0~161.0℃
Damnum in Siccatio <1.00%
Totalis immunditias <2.0%
Infrared Imaginis Conformat ut Structure
Proton NMR Spectrum Conformat ut Structure
Test Standard Enterprise Standard
Consuetudinem Medium de Mesylate Lenvatinib (CAS: 857890-39-2)

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

1

FAQ:

Applicatio:

Methyl 4-Amino-2-Methoxybenzoate (CAS: 27492-84-8) adhiberi potest ut medium mesylate Lenvatinib (CAS: 857890-39-2).Lenvatinib est medicamentum thyreoidum pharmacum ab Eisai Corporatione Iaponiae (Codex: E7080) inhibitoris multi-receptoris tyrosini kinasi (RTK) inhibitoris pertinens ac kinasum activitatem endothelialem factoris (VEGF) receptoribus VEGFR1 inhibere potest. FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4).Lenvatinib etiam impedire potest implicationem aliorum RTKs in angiogenesi pathologica, tumore augmento, et progressu cancri, exceptis functionibus normalibus cellularum inclusis fibroblast aucti (FGF) receptores FGFR1, II, III, IV;factor augmentationis receptae (PDGFR [alpha]), KIT, RET.[Indicationes]: Lenvatinib apta est curatione aegrorum cancri thyroideae localis recursu vel metastasi speciei, progressionis generis et iodi-refractionis radioactivi speciei differentiatae.Die 13 Februarii 2015, US FDA approbavit anticancer medicamentum Lenvatinib ad curationem cancri thyreici.Lenvatinib inhibitor enzyme multiplex est, cum possit inhibere VEGFR2 et VEGFR3 (vascularis incrementi endothelialis factor receptor).Nomen artis Lenvatinib est Lenvima.Die XX mensis Maii anno MMXV, Medicinae Europaeae Agency (EMA) Lenvatinib approbavit ad curationem incursionis, localiter progressae vel metastaticae differentiatae (papillaris, follicularis, generis Hurthle) cancri thyreici (DTC).In iudicio, media salus tempus aegris radioactivi Iodi-refractionis DTC tractatum cum Lenvatinib fuit XVIII mensium, dum valor aegrorum qui placebo capiuntur tantum 3 mensium est.

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