Olopatadinum Hydrochloridum intermedium CAS 27710-82-3 Puritas >99.0% (HPLC)

Description:

[3-(Dimethylamino)propyl] triphenylphosphonium Bromide Hydrobromide

CAS: 27710-82-3

Puritas: >99.0% (HPLC)

Aspectus: Alba ad Off-White Crystal pulveris

Intermedia Olopatadini Hydrochloridis (CAS 140462-76-6)

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Descriptio:

Chemical Properties:

Nomen chemicum [3-(Dimethylamino)propyl] triphenylphosphonium Bromide Hydrobromide
Synonyma (3-Dimethylaminopropyl) triphenylphosphonium Bromide HBr
CAS Number 27710-82-3
CATTUS Number RF2698
Stock Status In Stock, Productio Ascendite ad Tons
Formulae hypotheticae C23H28Br2NP
M. Pondus 509.27
Liquescens punctum 283.0~285.0℃
Stabilitas Hygroscopic
Solubilitas Chloroform (paulo), Methanol (paulo)
Brand Ruifu Chemical

Specifications:

Item Specifications
Aspectus White ad Off-Crystal pulveris
Puritas / Analysis Methodus >99.0% (HPLC)
Asssay / Analysis Methodo >99.0% (Titration)
Damnum in Siccatio <0.50%
una immunditia <0.50%
Totalis immunditias <1.00%
1 H NMR Spectrum Congruunt cum Structure
Test Standard Enterprise Standard
Consuetudinem Medium Hydrochloridis Olopatadinum (CAS: 140462-76-6)

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

Satis capacitas: sufficientes facilities et technici

Professional Service: One stop acquireing service

Altera Package: Custom sarcina ac titulus praesto

Ieiunium Delivery: Si intra stirpem, tres dies partus praestatur

Supple firmum: Esse rationabile stirpe

Technical Support: Technology solution praesto

Custom Synthesis Service: Range from P. to kilos

High Quality: Constitutus ratio completa qualitas certitudinis

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Qualitasfides?Qualitas strictioris temperantiae ratio.Pro instrumento analysi professionali includuntur NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Claritas, Solubilitas, Microbialis limes test, etc.

Exempla?Pleraque producta praebent exempla gratuita pro qualitate aestimationis, sumptus naviculas a clientibus solvendos.

Factory Audit?Factory audit gratissimum.Quaeso ante constitutum.

MOQ?Nec MOQ.Parvus ordo placet.

Tempus adferendi? Si intus prosapia, tres dies partus praestatur.

Transportatio?Per Express (FedEx, DHL), ab Air, per Mare.

Documenta?Post servitium venditionis: COA, MOA, ROS, MSDS, etc. praeberi possunt.

Consuetudo Synthesis?Consuetudo synthesis officia praebere potest ad optimas investigationes tuas necessitates aptandas.

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Applicatio:

[3-(Dimethylamino)propyl]triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) est intermedium Olopatadini hydrochloridis (CAS: 140462-76-6).Olopatadinum hydrochloridum medicamentum anti-allergicum est.Effectus duplices habet inhibendi emissione histaminis et selective repugnantis receptoribus HI, nec habet systema nervosum centrale inhibitionis et cardiaci toxici lateris effectus communes cum III receptore contra pharmaca antiallergica.Olopatadinum hydrochloridum non solum solutionem histaminis a cellulis malii inhibere potest, sed etiam receptores H1 magis selectos infestare, nec in α receptoribus adrenergicis, dopamine receptoribus, et M1 et M2 receptoribus nullum effectum habet.Inter eos, effectus laterum systematis nervosi centralis pauci sunt, est nova generatio medicamentorum antiallergicarum electionis.Olopatadinus est potens, selectivus antagonista histamine receptoris H1 (Ki = 16-41.1 nM), cum affinitatibus multo inferioribus receptoribus H2 et H3 (Ki = 43.4 et 172 µM, respective).Tumoverum phosphoinositidem in cellulis solitariis impedit (IC50 = 9.5-39.9 nM) et prohibet passivam cutaneam anaphylaxem in muribus (ED50 = 49 μg/kg) et anaphylacticam bronchoconstrictionem in Guinea porcorum (ID50 = 30 μg/kg).Olopatadine efficax est in tractandis allergicis rhinitis et conjunctivitis.Prodest etiam psoras urticaria inveterata bene temperata.In hominibus, hoc antihistamentum non causat deminutionem cognitivam vel psychomotoris in dosibus therapeuticis.

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