Palbociclib CAS 571190-30-2 Puritas >99.5% (HPLC) API Factory
Ruifu Chemical Supple Palbociclib Intermedia:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidines CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl) piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-pyridyl) piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H)-one CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyrimidin-7-one CAS 1013916-37-4
Nomen chemicum | Palbociclib |
Synonyma | PD-0332991;Otava-Bb 1115529;Ibrance |
CAS Number | 571190-30-2 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C24H29N7O2 |
M. Pondus | 447.54 |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba vel Off-White pulveris |
1H NMR Imaginum | Congruunt cum Structure |
HPLC | Congruunt cum Structure |
Substantiae cognatae | |
Individual Impurity | <0.50% |
Totalis immunditias | <1.00% |
Damnum in Siccatio | <0.50% |
Residere in Ignition | <0.10% |
Metalla gravis | <10ppm |
Puritas / Analysis Methodus | >99.5% (HPLC) |
Test Standard | Enterprise Standard |
Consuetudinem | API, De curatione Cancri |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore
Palbociclib (CAS: 571190-30-2) ore promptum est kinasum cyclinum-dependens (CDK) inhibitor cum actione antineoplastica potentiale.Palbociclib selective vetat cyclino-dependens kinasum 4 (CDK4) et 6 (CDK6), inde inhibuit retinoblastoma (Rb) interdum phosphorylationem mane in G1 periodo ducens ad cyclum cellulam comprehensionem.Haec DNA replicationem supprimit et multiplicationem cellae tumoris decrescit.Palbociclib primus est repraesentativus novi generis medicamentorum cyclin-dependens inhibitores kinasi.Hic effectus terminat prolificationem cellulae (Cellae incrementum et divisionem).Ponitur pro agente antineoplastico in cancer provectus vel metastaticus pectoris.