Posaconazole CAS 171228-49-2 API Triazole Antifungal Agens Quality
Factory Supple Posaconazole intermedia, Commercial Productio
Posaconazole CAS 171228-49-2
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Nomen chemicum | Posaconazole |
Synonyma | POS;SCH 56592;4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl] methoxy] phenyl] piperazin-1-yl] phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one |
CAS Number | 171228-49-2 |
CATTUS Number | RF-API77 |
Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
Formulae hypotheticae | C37H42F2N8O4 |
M. Pondus | 700.78 |
Density | 1.36 g/cm3 |
Solubilitas | Solutum in DMSO, insolubile in aqua |
Shipping Condition | Uit sub Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White Crystalline pulveris |
Lepidium sativum | IR: Imaginum producti effusio ultrarubrum consentaneum esse debet cum substantiae relationis |
Lepidium sativum B * | HPLC retentionis tempus similis referat substantiam |
Liquescens punctum | 167.0~171.0℃ |
Imprimis Rotationes [a]20 | -24.0° ~ -28.0° (C=1, CHCL3). |
Aquae (KF) | ≤1.0% |
Residere in Ignition | ≤0.10% |
Substantiae cognatae | |
HT 909-24 | ≤0.20% |
Omnis immunditia | ≤0.10% |
Totalis immunditias | ≤1.0% |
RELICTUM Solvents | |
Methanol | ≤3000ppm |
Methyl tert-Butyl Ether | ≤5000ppm |
Isopropanol | ≤5000ppm |
Dimethyl Sulfoxide | ≤5000ppm |
Dichloromethane | ≤600ppm |
Assay | 98.0% ~ 102.0% (Ratio in exaruit basis) |
Metalla gravis | ≤10ppm |
Isomer | Enantiomer ≤0.10% |
Singula immunditia ≤0.10% | |
Totalis immunditias ≤1.0% | |
Test Standard | Enterprise Latin;USP;BP;EP Standard |
Consuetudinem | API, Triazole Antifungal Agent |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
Posaconazole (CAS 171228-49-2), est latum-spectrum, secunda generatio, triazolum compositum cum actione antifungal, in UK inmissa, membrum novissimum azoli classium agentium antifungalorum ad forum attingendum.Demonstretur curatione et prophylaxi contagiosorum invasivorum fungalorum, incluso aspergillosi, fusariosi, chromoblastomycosi, mycetoma, et coccidiomycosi in aegros refractorio vel impatientes, norma therapia cum amphotericino B et/vel itraconazolo.In US, approbatur prophylaxi incursionis Aspergilli et Candidae contagione in aegris 13 annos aetatis, qui in magno periculo sunt evolutionis istarum contagionum ob graviter immunocompromissorum.Accedit ad oropharyngei tractationem approbatur candidiasis.Posaconazolus spectrum expansum actionis super alia membra antifungalorum azolorum habet.Praeter actionem potentem contra refractiores casus aspergillosis et fluconazoli Candidae renitentes, actionem contra Zygomycetem demonstrat.Posaconazole est triazolum antifungal pharmacum in Civitatibus Foederatis mercatum in Civitatibus Foederatis a Schering-Aro sub commercii nomine Noxafil.