Pregabalin CAS 148553-50-8 Puritas >99.0% (HPLC) Antiepileptica API
Manufacturer cum High puritate et Commercial Productio
Nomen chemicum: PregabalinCAS: 148553-50-8
Pregabalin est secunda generatio medicamento antiepileptico (AED)
Nomen chemicum | Pregabalin |
Synonyma | (S) -3-(Aminomethyl) -5-Methylhexanoic Acidum;PD-144723;PD144723;CI 1008;CI-CVIII;Lyrica |
CAS Number | 148553-50-8 |
CATTUS Number | RF-API57 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C8H17NO2 |
M. Pondus | 159.23 |
Liquescens punctum | 194.0~ 196.0℃ |
Solubilitas in aqua | Fere insolubilis in aqua |
Solubilitas | Leviter solutum in Ethanol |
Shipping Condition | Sub Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White Crystalline pulveris |
Lepidium sativum | IR: Similia Reference substantia |
Imprimis Rotationes | +0.0°~ + 13.0° (C = I, Aqua) |
Damnum in Siccatio | <0.50% |
Cinere sulphated | <0.10% |
Substantiae cognatae | immunditiam A <0.15% |
Impurities Eluting Ante Pregabalin (test A) <0.10% | |
Impurities Eluting Post Pregabalin ( test B ) <0.10% | |
Summa pro test A et B <0.50% | |
Puritas per HPLC R-Isomer | <0.15% |
Metalla gravia (ut Pb) | <10ppm |
Chlorides (Cl) | <0.05% |
RELICTUM Solvents | |
Isopropyl Sin | <5000ppm |
Ethyl Acetate | <5000ppm |
Tetrahydrofuran | <250ppm |
Isopropyl Ether | <500ppm |
Ethanol | <1000ppm |
Puritas / Analysis Methodus | > 99.0% (HPLC in exaruit basis) |
Test Standard | Enterprise Standard |
Consuetudinem | Medicamentum antiepilepticus API |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine & humore
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Pregabalin pharmacum antiepilepticum secundae generationis (AED) notae proprietatis notae nomine Lyricae (Pfizer, Tadworth) in UK et USA est, habens γ-aminum butyricum structuram acidi in structura sua hypothetica, quae effectus anticonvulsantes habet, et est. societas Pfizer feliciter evoluta est ad curationem doloris peripherici neuropathici, seu curationi partialis invasiones adjuvans.Pregabalin est medicamentum anticonvulsans et antiepilepticus, quo usus est ad curandum epilepsiam, dolorem neuropathicum, fibromyalgia, et inordinationem anxietatis communis.Usus ad epilepsiam est sicut therapiam addendi pro captionibus partialibus cum vel sine generalizatione secundario in adultis.Mense Decembri 2008, US Cibus et Administration medicamentis (FDA) approbavit pregabalin (nomen artis "Lyricae") ad curationem diabetici doloris peripherici neuropathici (DPN) et neuralgiae postherpeticae (PHN) quae sunt ambo frequentissimi dolores neuropathici.Pregabalin probatum indicium habet et late adhibetur ad curationem perturbationis anxietatis communis.Plures randomized, geminus-caecus, tentationes placebo continentes invenerunt pregabalin efficacem esse curationem aegrorum cum anxietate generativa inordinationis et anxietatis socialis inordinationis.Dosis titrationi epilepsiae-adiunctivae therapiae: 25 mg bd pro 7 diebus, augenda per 50 mg singulis diebus 7;consueta conservatio 300 mg cotidie, in 2 vel 3 doses divisa (max. 600 mg cotidie, in 2 vel 3 doses divisa).Sollicitudo inordinatio generativa: 150 mg cotidie, in 2 vel 3 dosibus divisa, per 7 dies, ut 150 mg per 7 dies augeatur (max. 600 mg cotidie, in 2 vel 3 gustatu dividitur).Si pregabalin reprimendo, commendatur ut per 1 saltem hebdomadam cereus fiat, ne recessus abruptus sit.Cautiones aegroti cum conditionibus encephalopathia praecipitare possunt.Aegris cum gravibus congestivis cordis defectum.
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