Ramelteon Medium 12 CAS 1053239-39-6 Puritas >98.0% (HPLC)

Description:

Nomen chemicum: 2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride

Synonyma: Ramelteon medium 12

CAS: 1053239-39-6

Puritas: >98.0% (HPLC)

Aspectus: Alba ad Off-White solidus pulveris

Ramelteon (CAS: 196597-26-9)

Contactus: Dr

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E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Descriptio:

Ducens Manufacturer et Supplier, intermedia Ramelteonis
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloridum CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Chemical Properties:

Nomen chemicum	2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride
Synonyma	Ramelteon Intermediate 12;Ramelteon Stage-2 Impurity;1,6,7,8-Tetrahydro-2H-Indeno[5,4-B] Furan-8-Ethanamine Hydrochloride
CAS Number	1053239-39-6
CATTUS Number	RF2887
Stock Status	In Stock, Productio Ascendite ad Tons
Formulae hypotheticae	C13H18ClNO
M. Pondus	239.74
Liquescens punctum	165.0~167.0℃
Density	1.058±0.06 g/cm3
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Aspectus	White ad Off-White solidus pulveris
Puritas / Analysis Methodus	>98.0% (HPLC)
Damnum in Siccatio	<1.00%
una immunditia	<1.00%
Totalis immunditias	<2.00%
1 H NMR Spectrum	Congruunt cum Structure
Test Standard	Enterprise Standard
Consuetudinem	Ramelteon (CAS: 196597-26-9)

Sarcina & Repono:

sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris

Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine et humore

commoda:

Satis capacitas: sufficientes facilities et technici

Professional Service: One stop acquireing service

Altera Package: Custom sarcina ac titulus praesto

Ieiunium Delivery: Si intra stirpem, tres dies partus praestatur

Supple firmum: Esse rationabile stirpe

Technical Support: Technology solution praesto

Custom Synthesis Service: Range from P. to kilos

High Quality: Constitutus ratio completa qualitas certitudinis

FAQ:

Quam mercari?Quaeso contactumDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience?Plus quam XV annos experientiae habemus in fabricando et exportando amplis intermediis pharmaceuticis vel alchimicis pharmaceuticis amplis.

Mercatus principalis?Vendere mercatum domesticum, Americam septentrionalem, Europam, Indiam, Coream, Iaponicam, Australiam etc.

Commodi?Superior qualitas, parabilis pretium, officia professionalia et subsidia technica, ieiunium partus.

Qualitasfides?Qualitas strictioris temperantiae ratio.Pro instrumento analysi professionali includuntur NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Claritas, Solubilitas, Microbialis limes test, etc.

Exempla?Pleraque producta praebent exempla gratuita pro qualitate aestimationis, sumptus naviculas a clientibus solvendos.

Factory Audit?Factory audit gratissimum.Quaeso ante constitutum.

MOQ?Nec MOQ.Parvus ordo placet.

Tempus adferendi? Si intus prosapia, tres dies partus praestatur.

Transportatio?Per Express (FedEx, DHL), ab Air, per Mare.

Documenta?Post servitium venditionis: COA, MOA, ROS, MSDS, etc. praeberi possunt.

Consuetudo Synthesis?Consuetudo synthesis officia praebere potest ad optimas investigationes tuas necessitates aptandas.

Pensio conditio?Proforma cautionis primum post confirmationem ordinis mittetur, informationes nostrae ripae inclusas.Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Applicatio:

2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethanamine Hydrochloridi (CAS: 1053239-39-6) medium est Ramelteonis (CAS: 196597- 26-9).Dissimiles plurimae curationes insomnia, quae GABA (g-aminobutyric acid) receptantis complexi oppugnant, Ramelteon est agonista receptoris melatonini.Praesertim cum subtyporum MT1 et MT2 summa selectivity, quae in rhythmis circadianis conservandis implicata est, super receptorem MT3 aliarum functionum melatoninorum responsales habet.Defectus affinitatis ad non solum receptatores complexi GABA, sed etiam receptores neurotransmitterae, dopaminerigici, opiatae, et benzodiazepini receptatores praebet meliorem salutem profile expertem abusus potentiae medicamentorum hypnoticorum qui hos receptores oppugnant.Ut, Ramelteon medicamento non accedant.Metabolitae primariae hydroxylationem et oxidationem in speciebus carbonyli includunt cum metabolitis secundariis ex glucuronidatione provenientes.Cum CYP1A2 sit maior isozyma in metabolismo hepatico Ramelteonis implicata, non debet sumi in inhibitoribus validis CYP1A2, ut fluvoxaminum.Co-administratio cum vel ketoconazola (a CYP3A4 inhibitoris) vel fluconazoli (potens CYP2C9 inhibitoris) consecuta est in auctis significantibus in AUC et Cmax, sed metabolismi ampla et valde variabilis plasmatis concentrationis Ramelteonis necessitatem dosis modificationis praeclusit.Involucrum tamen inhibitores cautiones aegros de coadministratione potenter CYP3A4 et CYP2C9 cautiones habent.Ex evento iudiciorum clinicorum, suadeo dosis Ramelteonis intra 30 min cubitum sumpta est.Praeter cautelam co-administrationis cum CYP inhibitoribus, adhibenda non est in aegris gravibus hepatis incommodis.Res adversae, quae in studiis clinicis aegrorum observatae sunt, somnus, vertigo, nausea, lassitudo, capitis, vigiliae erant.