(S) -3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Puritas ≥99.0% ee≥99.0% Palonosetron Hydrochloridum intermedium
Commercial Supple Palonosetron Hydrochloride et intermedia Related:
(S) 1,2,3,4-Tetrahydro-1-Naphthoicum Acidum CAS: 85977-52-2.
(R) 1,2,3,4-Tetrahedro-1-Naphthoicum Acidum CAS: 23357-47-3
(S) -3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinonis Hydrochloridis CAS: 1193-65-3
1-Naphthoicum Acidum CAS: 86-55-5
Palonosetron Hydrochloridum CAS: 135729-62-3 API
Nomen chemicum | (S) -3-Aminoquinuclidine Dihydrochloride |
Synonyma | (S)-(-)-3-Aminoquinuclidine 2 HCL |
CAS Number | 119904-90-4 |
CATTUS Number | RF-CC112 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C7H16Cl2N2 |
M. Pondus | 199.12 |
Density | 1.24g/cm3 |
Liquescens punctum | 260℃ |
Ferveret | 470.4℃ ad 760mmHg |
Solubilitas in aqua | Solubilis |
Shipping Condition | Uit sub Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad lux Yellow Crystalline pulveris |
IR | Effusio spectris congruens cum Reference |
Chloride reactionem | Positivum Reactionem |
Munditia (HPLC) | ≥98.0% |
Damnum in Siccatio | ≤0.50% |
Imprimis Rotationes [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
Metalla gravis | ≤20ppm |
Repono | 5-8℃ Airtightness |
Test Standard | Enterprise Standard |
Consuetudinem | Palonosetron Hydrochloridum (CAS: 135729-62-3) Intermedia |
(S) -3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Synthetica Route
sarcina: Utrem, aluminium foil, pera, cardboard Drum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Protege a lumine, humore et pestis infestatione.
Shanghai Ruifu Chemical Co., Ltd. est primarium fabricae et elit (S)-3-Aminoquinuclidinae dihydrochloridis (CAS: 2133-40-6) cum qualitate alta.Medium pharmaceuticum typice in synthesi Palonosetron hydrochloridi (CAS: 135729-62-3).
Palonosetron hydrochloridum (CAS: 135729-62-3) medicamentum est ad nauseam et vomitum inhibendum, quod novum genus est valde selectivum, summus affinitatis receptor 5-HT3, qui vomitum reflexum centrum peripheralium neuronum presynapticum 5-HT impedire potest.Receptor incitationis systematis nervosi centralis directe afficit in 5-HT.Impetus receptoris concitationis generatae per partes nervi vagalis afferentis post aream, claudebant terminationes vagi in ventrem, ne signa ad 5-HT.Receptor felis zonam incidentiam nauseam et vomitum reducere potest.Centralis amet ad curationem chemotherapy emetogenicam acrem acrem inductum, nauseam et vomitum differri.Propter altitudinem curativam effectus, parum latus effectus, longa dimidia vita (circiter 40 h), parva dosis, et sic porro, multum attendit.Cum acido 1,2,3,4-tetrahydro-1-naphthoico ut materia principii, scissura, aminatione, reductione, cyclizatione, sal palonosetron hydrochloridi granisetron.Studia clinica demonstraverunt palonosetron tuto adhiberi posse cum corticosteroideis, analgesicis, antiemeticis, antispasmodicis et anticholinergicis medicamentis initio materiae, scissurae, aminationis, reductionis, cyclizationis, sal palonosetron hydrochloridi granisetron.