Sitagliptin Phosphate Monohydrate CAS 654671-77-9 Puritas >99.0% (HPLC) API Factory High Quality
Supple Sitagliptin Phosphate Monohydratorum intermedia:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydratum API CAS 654671-77-9
Acidum trifluorophenylaceticum 2,4,5-
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acidum CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydratum Intermediate CAS 486460-21-3
Nomen chemicum | Sitagliptin Phosphate Monohydrate |
Synonyma | (R) -3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4- phosphate monohydrate |
CAS Number | 654671-77-9 |
Stock Status | In Stock, Productio Ascendite ad Tons |
Formulae hypotheticae | C16H20F6N5O6P |
M. Pondus | 523.3240802 |
Liquescens punctum | 202.0~204.0℃ |
Aqua Solubility | Solutum in aqua |
Imprimis Rotationes | -18.0°~-23.0° (C=I, Aqua) |
Brand | Ruifu Chemical |
Item | Specifications |
Aspectus | Alba ad Off-White Crystalline pulveris |
Lepidium sativum ab HPLC | Retention tempus specimen concordat cum reference vexillum |
IR-Infrared Imaginum | IR Absorptio Imaginis sample concordabit cum spectro normali |
Phosphate | Obsequitur |
Puritas / Analysis Methodus | > 99.0% (HPLC in exaruit basis) |
Aqua Content (KF) | 3.3%~4.4% |
Residere in Ignition | ≤0.20% |
Sulphate | ≤0.04% |
Chloride | ≤0.05% |
Chiral immunditia | <0.50% |
Substantiae cognatae | |
una immunditia | <0.50% |
Totalis immunditias | <1.0% |
Ethyl Acetate | <0.50% |
Metalla gravis | <20ppm |
Test Standard | Enterprise Standard |
Consuetudinem | Pharmaceutical intermedia |
sarcina: Utrem, aluminium foil, sacculum, 25kg/cardboard Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;A luce et humore protege.
Sitagliptin Phosphate Monohydratorum (CAS: 654671-77-9), novum medicamentum ad curationem diabete generis 2 .Mense Augusto 2009 pharmacum ab Unione Europaea probatum est tamquam medicamentum primae lineae pro curatione speciei 2 diabete.Sitagliptin Phosphate primus est FDA-probatus dipeptidylus peptidase-IV inhibitor adhibendus in tractatione speciei 2 diabete longe, sub commercii nomine Januvia.Dipeptidylpeptidase Ⅳ (DPP-Ⅳ) celerius et efficaciter detractat GLP-1, GLP-I, quae est efficacissima stimulator productionis et secretionis insulinae, inhibitio ergo DPP-IV partes endogenosae GLP-1 augere potest, sanguinem augens. insulinum gradus, ita reducere et conservare sanguinem GLYCOSA aequat in aegris diabeticis.In praesenti medicina confirmavit DPP-IV inhibitorem novum genus medicamentorum anti-diabetici esse, et eventus clinicos demonstrant medicinae effectum bonum hypoglycemicum habere.Quia GLP-1 dependens partes glucose-dependens agit in productione et secretione insulina promovenda, motus communes adversas sicut hypoglycemia et lucrum pondus causatum ex usu medicamentorum antidiabeticorum non occurrunt.