Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API
Supple Vonoprazan Fumarate ac Related medium
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Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Nomen chemicum | Vonoprazan Fumarate |
| Synonyma | TAK-438 |
| CAS Number | 1260141-27-2;881681-01-2 |
| CATTUS Number | RF-API99 |
| Stock Status | In Stock, Productio Ascendite usque ad Centum chiliogrammata |
| Formulae hypotheticae | C21H20FN3O6S |
| M. Pondus | 461.463 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Aspectus | Alba aut fere-alba crystallina pulveris |
| Lepidium sativum I H-NMR | Congruunt cum Latin |
| Lepidium sativum IR | IR Absorptio spectri specimen concordantium cum reference vexillum |
| Lepidium sativum HPLC | Retentione temporis specimen concordantium cum reference vexillum |
| Aqua Content | ≤0.50% |
| Residere in Ignition | ≤0.20% |
| Metalla gravia (ut Pb) | ≤20ppm |
| Substantiae cognatae | |
| immunditiam A | ≤0.20% |
| impudicitia B | ≤0.15% |
| immunditia C | ≤0.15% |
| Alia immunditia | ≤0.10% |
| Totalis immunditias | ≤1.0% |
| RELICTUM Solvents | |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| Ethyl Acetate | ≤0.50% |
| Asssay / Analysis Methodo | 98.0%~ 102.0% (By HPLC) |
| Test Standard | Enterprise Standard |
| Consuetudinem | API |
sarcina: Utrem, aluminium foil, pera, cardboard tympanum, 25kg/Drum, vel secundum exigentiam emptoris.
Repono Condition:Repone in vasis signatis in loco frigido et sicco;Lucem protege, humorem.
Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), proton antliae inhibitoris (PPI), est potassa et viva potassae-competitiva cum antisecretorio (P-CAB), cum antisecretorio actione.Vonoprazan Fumarate inhibet H+,K+-ATPase activitatem in microsomes gastrica porcina cum IC50 19 nM ad pH 6.5.Vonoprazan Fumarate (Takecab), inventa et evoluta ab Takeda et Otsuka, ab PMDA Iaponiae probata est mense Decembri anno 2014. Vonoprazan Fumarate maxime adhibetur ad contagionem pylori curationem helicobacteri, reflux gastroesophagi, ulceris peptici, ulceris duodeni, esophagitis, gastrici. ulceris gastrici et aliorum morborum affinium acidorum.Productum inhibitionis gastrici acidi secretionis fortis et diuturnae habet.In curatione dosis, Vonoprazan Fumarate parum valet in aliis enzymis et in physiologicis corporis functionibus parum effectus.Tutius est et tolerabilius.
