Manufactur standard Irinotecan Hydrochloride Intermediate - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu
Manufactur standard Irinotecan Hydrochloride Intermediate - 2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factory – Ruifu Detail:
Manufacturer Supply, High Purity, Commercial Production
Chemical Name: 2-Chloroadenine
CAS: 1839-18-5
Chemical Name | 2-Chloroadenine |
Synonyms | 6-Amino-2-Chloropurine; Cladribine EP Impurity B |
CAS Number | 1839-18-5 |
CAT Number | RF-PI513 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C5H4ClN5 |
Molecular Weight | 169.57 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Yellowish to Off-White Powder |
Assay / Analysis Method | ≥98.0% (HPLC) |
Melting Point | ≥300℃ |
Loss on Drying | ≤0.50% |
Residue on Ignition | ≤0.50% |
Heavy Metals (as Pb) | ≤0.001% |
Total Impurities | ≤2.0% |
Test Standard | Enterprise Standard |
Usage | Intermediate of Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer’s requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
2-Chloroadenine (CAS: 1839-18-5) is mainly used as intermediate of Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8) and other APIs. Clofarabine is a novel purine nucleoside anticancer drugs is first successfully developed by the Top10 biopharmaceutical company of the United States-Genzyme Corporation. On December 28, 2004 the US food and Drug Administration (FDA) used fast-track for approval of clofarabine for application to children with refractory or relapsed acute lymphocytic leukemia. Cladribine (2-chloro-2′-deoxyadenosine) is an adenosine deaminase-resistant analogue of deoxyadenosine. The drug has a broad range of in vitro activity against both lymphoid and myeloid neoplasms.
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