Manufacturing Companies for N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanine - 2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9 Dapagliflozin and Canagliflozin Intermediate – Ruifu

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (CAS: 32384-65-9) is usually used as the intermediate and raw material in the chemistry synthesis and pharmaceutical industry. Especially, this chemical has been widely used in the design and synthesis of sodium-glucose transporter inhibitors. For example, this substance can be employed as raw material in the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxylphenyl)methyl]phenyl]-D-glucitol, which is commonly known as Dapagliflozin(CAS: 461432-26-8) that act as the sodium dependent glucose transporters for treating type 2 diabetes. Moreover, it can also function as the intermediate for synthesizing Empagliflozin, which is a novel and selective sodium glucose co-transporter-2 inhibitor. In addition, Canagliflozin (CAS: 842133-18-0), another sodium glucose co-transporter-2 inhibitor, can be obtained by utilizing this substance as the intermediate.