Sitagliptin Phosphate Intermediate Impurity CAS 769195-26-8 Purity >99.0% (HPLC)

Short Description:

Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate

CAS: 769195-26-8

Purity: >99.0% (HPLC)

Appearance: White to Off-White Powder

Intermediate / Impurity of Sitagliptin Phosphate 

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E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate (CAS: 769195-26-8) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate 
Synonyms Sitagliptin Impurity 17; 2,4,5-Trifluoro-β-Oxo-Benzenebutanoic Acid Methyl Ester 
CAS Number 769195-26-8 
CAT Number RF2656
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C11H9F3O3 
Molecular Weight 246.18 
Melting Point 40.0~41.0℃
Boiling Point 273.3±35.0℃
Density 1.330±0.06 g/cm3
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Purity / Analysis Method >99.0% (HPLC) 
Loss on Drying <1.00%
Single Impurity <0.50%
Total Impurities <1.00%
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Intermediate / Impurity of Sitagliptin Phosphate

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

Methyl 3-Oxo-4-(2,4,5-Trifluorophenyl)butanoate (CAS: 769195-26-8) is a useful synthetic intermediate in the synthesis of Sitagliptin (CAS: 486460-32-6), Sitagliptin Phosphate (CAS: 654671-78-0). Sitagliptin Phosphate is dipeptidyl peptidase Ⅳ(DDP-4) inhibitor class of drugs developed by the German Merck company and firstly obtained the US Food and Drug Administration approval for the treatment of type 2 diabetes, is a new antidiabetic drug, can improve the body's own ability to reduce high blood glucose levels, and the relatively increase naturally occurring incretin by inhibiting the activity of this enzyme, including the levels of glucagon-like peptide 1 and glucose-dependent insulinotropic peptide, thereby triggering the pancreas to improve insulin production and stop glucose production in liver, and ultimately reduce the clinical effect of blood glucose concentration.

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