1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3 Purity >98.0% (HPLC) Brexpiprazole Intermediate Factory
Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-kotahi CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Ingoa matū | 1-(1-Benzothiophen-4-yl)piperazine Hydrochloride |
Nga kupu taurite | Brexpiprazole Intermediate 2;1-Benzo[b]thien-4-yl-Piperazine Hydrochloride;1-Benzo[b]thien-4-ylpiperazine Monohydrochloride |
Tau CAS | 913614-18-3 |
Tau CAT | RF-PI1034 |
Tūnga Taonga | I roto i te Raarangi, Te Whakaputa Whakanui 100MT / Tau |
Tātai rāpoi | C12H15ClN2S |
Taumaha rāpoi | 254.7789 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura-White |
Tautuhinga | Ko te wa pupuri o te tauira ka rite ki tera o te paerewa tohutoro |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Ngaronga i te whakamaroke | <0.50% |
Wai (KF) | <0.50% |
Te toenga i runga i te mura | <0.20% |
Nga Taonga Paanga | (HPLC) |
Te poke takitahi | <0.50% |
Nga poke katoa | <1.00% |
Spectrum Infrared | He rite ki te Hanganga |
Proton NMR Spectrum | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Brexpiprazole (CAS: 913611-97-9) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te 1-(1-Benzothiophen-4-yl)piperazine Hydrochloride (CAS: 913614-18-3) he takawaenga o Brexpiprazole (CAS: 913611-97-9).Ko te Brexpiprazole he momo antipsychotic atypical.Ko te dopamine D2 kaiawhina agonist waahanga.Hei tauira mo te rerotonin-dopamine mahi modulator, ka taea te whakamahi mo te maimoatanga o te schizophrenia, mo te maimoatanga taapiri mo te pouri.Ka taea hoki te whakarato i te whaihua me te ngawari ki runga i nga maimoatanga taapiri kua whakaritea mo te mate pouri nui (MDD).Ko te tarukino e whakaatu ana i tetahi tohu rongoora ahurei, e mahi ana hei agonist wahanga o te serotonin 5-HT1A me te dopamine D2 receptors me te rite ki te tino antagonist o 5-HT2A me te noradrenaline α1B/2C receptors, he rite te hononga here subnanomolar.Ko te tarukino, i whakawhanakehia e Otsuka me Lundbeck, i whakaaetia i te 2015 e te FDA mo te maimoatanga o te schizophrenia me te maimoatanga taapiri mo te pouri.