(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Purity ≥99.0% Bortezomib Intermediate High Purity
Whakaratohia nga Kaiwawao e Pa ana ki te Bortezomib me te Maamaa
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7
| Ingoa matū | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
| Nga kupu taurite | (1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
| Tau CAS | 18680-27-8 |
| Tau CAT | RF-CC290 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C10H18O2 |
| Taumaha rāpoi | 170.25 |
| Wairewa | Chloroform, Toluene |
| Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Ma ki te Paura-White Tioataata Paura |
| Iwi Whakarewa | 56.0~59.0℃ |
| Ngaronga i te whakamaroke | ≤0.50% |
| Te toenga i runga i te mura | ≤0.50% |
| Te taikaha Enantiomeric | ee≥99.0% |
| Te Maama / Tikanga Tatauria | ≥99.0% (GC) |
| Hurihuri Tau [α]20/D | +8.5° ki te +9.5° (C=6.5, Toluene) |
| Spectrum Infrared | Ka rite |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Pūhui Hira;Takawaenga Rongoa;Bortezomib Intermediate |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) me te kounga teitei, e whakamahia nuitia ana i roto i te waro. te whakahiato, te whakahiatotanga o nga takawaenga rongoa me te whakahiato matū pai.
He mahi nui a Shanghai Ruifu Chemical Co., Ltd. i roto i te matū chiral, e u ana te kamupene ki te hanga i nga pūhui chiral.Ko a maatau hua e whakanuia ana e nga kaihoko.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), he reagent Chiral whaihua e whakamahia ana i roto i te whakahiato o te homochiral α-hydroxyketones me te whakatau i nga esters prolineboronate.He tohu whaihua ano mo te chiral allyl boronate e whakamahia ana hei whakareri i te chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) Ko te Takawaenga o Bortezomib (CAS 179324-69-7) i roto i te maimoatanga o Myeloma Maha.Ko te Bortezomib, he aukati ubiquitin proteasome (26S) kaha (Ki=0.6 nM), i whakarewahia i te US hei maimoatanga mo te myeloma maha.Ko tenei proteasome e hiahiatia ana mo te whakahekenga proteolytic o te nuinga o nga pūmua pūtau, kei roto i nga pūtau katoa.E hiahiatia ana mo te whakahaere i nga tukanga mumura, te whakaritenga huringa o te pūtau me te whakaaturanga ira, he kaupapa hou mo te maimoatanga mate pukupuku.
