2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Purity >99.5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Kaihanga Kaihanga, Te Kounga teitei me te Utu Whakataetae
Tipiracil Hydrochloride (CAS: 183204-72-0) Takawaenga Paanga
6-(Chloromethyl)uracil CAS: 18592-13-7
6-(Hydroxymethyl)uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
| Ingoa matū | 2-Amino-1-Pyrroline Hydrochloride |
| Nga kupu taurite | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
| Tau CAS | 7544-75-4 |
| Tau CAT | RF-PI1838 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C4H8N2·HCl |
| Taumaha rāpoi | 120.58 |
| Te Whakarewa | 171.0 ki te 175.0 ℃ |
| Tairongo | Hygroscopic |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga | Hua |
| Te ahua | Paura ma | Paura ma |
| Te Maama / Tikanga Tatauria | >99.5% (HPLC) | 99.8% |
| Nui Rawa Takitahi poke | <0.50% | 0.09% |
| Ihirangi wai (KF) | <0.50% | 0.45% |
| Proton NMR Spectrum | He rite ki te Hanganga | Ka rite |
| Paerewa Whakamatau | Paerewa hinonga | |
| Whakamahinga | Takawaenga o Tipiracil Hydrochloride (CAS: 183204-72-0) | |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te 2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) he pūhui organic heterocyclic, ka taea te whakamahi hei takawaenga rongoa.Ko te 2-Amino-1-Pyrroline Hydrochloride he takawaenga o Tipiracil Hydrochloride (CAS: 183204-72-0) i roto i te maimoatanga o te mate pukupuku Rectal.Ko te Tipiracil Hydrochloride he aukati kaha me te whakataetae o te thymidine phosphorylase (TPase) me te uara IC50 o 35 nM mo te TPase placental tangata.He mea whiriwhiri mo TPase i runga i etahi atu enzymes-metabolizing pyrimidine (IC50s => 1 mM mo UPase, OPRTase, TK, me DPDase).Ka aukati te TPI i te phosphorolysis me te paheketanga o te trifluorothymidine, he nucleoside cytotoxic, i roto i nga tauira pukupuku pukupuku mate pukupuku o te u me te koroni.Ko te whakahaere a-waha o te TPI (12.5-50 mg / kg) ka whakanui i te mahi anti-tumor o te trifluorothymidine i roto i te kiore AZ-521 tauira xenograft mate pukupuku puku.Kua whakamahia nga hanganga kei roto TPI mo te maimoatanga o te mate pukupuku colorectal metastatic.
