2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Purity ≥99.0% Pirfenidone Intermediate Factory
Kaihanga Kaihanga, Te Maamaa Teitei, Te Hanga Aromoni
Ingoa matū: 2-Hydroxy-5-Methylpyridine
CAS: 1003-68-5
| Ingoa matū | 2-Hydroxy-5-Methylpyridine |
| Nga kupu taurite | 5-Methyl-2(1H)-Pyridinone;2-Hydroxy-5-Picoline;6-Hydroxy-3-Picoline;5-Methyl-2-Pyridinol |
| Tau CAS | 1003-68-5 |
| Tau CAT | RF-PI549 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C6H7NO |
| Taumaha rāpoi | 109.13 |
| Te Whakarewa | 183.0 ki te 187.0 ℃ (marama) |
| Wairewa | Wairewa ki Methanol |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Paura-White ki te Paura Tioata Kowhai |
| Maamaa | ≥99.0% |
| Ihirangi makuku (KF) | ≤0.50% |
| Te toenga i runga i te mura | ≤0.50% |
| Tetahi poke kotahi | ≤0.50% |
| Nga poke katoa | ≤1.00% |
| Wairewa toenga | |
| n-Butanol | ≤0.30% |
| Ewaro | ≤0.30% |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Takawaenga o Pirfenidone (CAS: 53179-13-8) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ka whakamahia te 2-Hydroxy-5-Methylpyridine (CAS: 1003-68-5) hei takawaenga rongoa o Pirfenidone (CAS: 53179-13-8).Ko te Pirfenidone (PFD) he momo hou o te pyridine ketones he huanga anti-fibrotic whanui, he kaha ki te aukati me te huri i te hanganga o te fibrosis me te nawe.I uru ki te maakete i Shionogi, Japan i te tau 2008, a kua whakaaetia e te US Food and Drug Administration.Koia te rongoa tuatahi kua uru ki nga whakamatautau haumanu i te wahanga III (tae atu ki te tukurua, te matapōkere, me te mana-placebo) e whakaatu ana i tana whai hua ki te rongoa i te fibrosis pulmonary idiopathic (IPF);i tua atu, he pai te kaha o te rongoa ki te rongoa i etahi mate fibrotic penei i te renal interstitial fibrosis me te ate fibrosis.
