2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5 Tolvaptan Intermediate Factory Kounga Teitei
Kaihanga Kaihanga, Kounga Teitei, Hanganga Aromoni
Tolvaptan me nga Takawaenga Paanga:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Waikawa CAS 1975-51-5
Ingoa matū | 2-Methyl-4-Nitrobenzoic Waikawa |
Nga kupu taurite | 4-Nitro-o-Toluic Waikawa;4-Nitro-2-Methylbenzoic Waikawa |
Tau CAS | 1975-51-5 |
Tau CAT | RF-PI397 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C8H7NO4 |
Taumaha rāpoi | 181.15 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Tata ki te Ma, te Kowhai Kowhai Kowhai ranei te paura tioata |
1H-NMR | E rite ana ki te Hanganga |
Te Maama / Tikanga Tatauria | ≥98.0% (HPLC) |
Te Whakarewa | 153.0~156.0℃ |
makuku (KF) | ≤0.50% |
Te toenga i runga i te mura | ≤0.50% |
Nga poke katoa | ≤2.0% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Tolvaptan (CAS 150683-30-0) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
Ko te 2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) ka whakamahia hei takawaenga rongoa i roto i te whakahiato o Tolvaptan (CAS 150683-30-0).Ko te Tolvaptan he kaipatu, he whakataetae arginine vasopressin receptor 2 antagonist me te IC50 o 1.28μM mo te aukati i te whakahiato pereti a AVP.Ka whakamahia te Tolvaptan ki te rongoa i te hyponatremia (nga taumata konutai toto iti) e pa ana ki te ngoikore o te ngakau, te cirrhosis, me te mate o te homoni antidiuretic tika (SIADH).I whakaaetia a Tolvaptan e te US Food and Drug Administration i te Mei 19, 2009, a ka hokona e Otsuka Pharmaceutical Co. i raro i te ingoa hokohoko Samsca.