2-Methyltryptamine CAS 2731-06-8 Purity >99.0% (HPLC) Panobinostat Intermediate Factory Kounga Teitei
Kaihanga Kaihanga Ki te Kounga Teitei, Hanganga Aromoni
Ingoa matū: 2-Methyltryptamine CAS: 2731-06-8
Ingoa matū | 2-Methyltryptamine |
Nga kupu taurite | 2-Methylindole-3-Ethylamine;2-(2-Methyl-1H-indol-3-yl)ethanamine;3-(2-Aminoethyl)-2-Methylindole |
Tau CAS | 2731-06-8 |
Tau CAT | RF-PI1480 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C11H14N2 |
Taumaha rāpoi | 174.25 |
Te Whakarewa | 106.0 ki te 110.0 ℃ |
Kohuatanga | 177 ℃/1.5mmHg(marama) |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paraone Mārō |
Te Maama / Tikanga Tatauria | >99.0% (HPLC Area) |
1-HNMR | E rite ana ki te Hanganga |
Ngaronga i te whakamaroke | <1.00% |
Te poke kotahi | <0.50% |
Nga poke katoa | <1.00% |
Konga Taamaha (hei Pb) | <20ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga Rongoa;Panobinostat Intermediate |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
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Ko te 2-Methyltryptamine (CAS: 2731-06-8) he mea timatanga matua i roto i te whakahiato o Panobinostat (LBH589) (CAS: 404950-80-7).Ko te Panobinostat he aukati kaha o nga histone deacetylases katoa (HDACs), me nga uara Ki mai i te 0.6 ki te 31 nM mo te HDAC1-11.Na roto i tenei mahi, ka arahi ki te acetylation o te whānuitanga o nga pūmua pūtau, ka mutu te hopukina huringa pūtau me te apoptosis i roto i nga pūtau mate pukupuku.Ko Panobinostat te tuatahi o te aukati HDAC i whakaaetia e te FDA mo te maimoatanga o te myeloma maha.Ko te Panobinostat te hokohoko hei Farydak, ka whakamahia ki te Bortezomib (CAS: 179324-69-7) me Dexamethasone (CAS: 50-02-2) ki te hamani i te mieloma maha kua hoki mai i muri i te maimoatanga o mua me Bortezomib me te immunomodulator.
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