2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Waenga Parakore >99.0% (GC)
Kaihanga Kaihanga me te Kaiwhakarato, Kaiwaenga o Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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| Ingoa matū | 2,3-Dihydrobenzofuran |
| Nga kupu taurite | Coumaran;2,3-Dihydro-2,3-Benzofuran;2,3-Dihydrobenzo[b]furan;2,3-Dihydro-1-Benzofuran |
| Tau CAS | 496-16-2 |
| Tau CAT | RF2884 |
| Tūnga Taonga | I roto i te Stock, Production Raukaha 20 Tons ia Marama |
| Tātai rāpoi | C8H8O |
| Taumaha rāpoi | 120.15 |
| Iwi Whakarewa | -21℃ |
| Kohuatanga | 188.0~189.0℃ (marama) |
| Tohu Kohiko | 66℃ |
| Wairewa | Waipiro: Wairewa |
| Tuhipoka morearea | Whakariri |
| TSCA | Ae |
| Waehere HS | 29329995 |
| Rokiroki Temp. | Hirihia ki te maroke, te pāmahana rūma |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Maama Te Wai Kowhai, Kowhai ranei |
| Te Maama / Tikanga Tatauria | >99.0% (GC) |
| Wai (na Karl Fischer) | <0.50% |
| Kiato (20℃) | 1.065~1.085 |
| Taupū Refactive n20/D | 1.547~1.551 |
| Te poke kotahi | <0.50% |
| Nga poke katoa | <1.00% |
| Proton NMR Spectrum | He rite ki te Hanganga |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Takawaenga Rongoa o Ramelteon (CAS: 196597-26-9) |
Mōkī: Pounamu Fluorinated, 25kg / Drum, kia rite ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Ko te 2,3-Dihydrobenzofuran (CAS: 496-16-2) e whakamahia nuitia ana i roto i te whakahiatotanga o nga pūhui tricyclic, a, he rauemi mata takawaenga hoki mo te whakahiato o etahi raau taero nui.Ka taea te whakamahi 2,3-Dihydrobenzofuran hei takawaenga o Ramelteon (CAS: 196597-26-9).Ko Ramelteon, i hokona hei Rozerem e Takeda Pharmaceuticals North America, he kaihoko moe e herea ana ki nga kaiwhakawhiwhi MT1 me MT2 i roto i te suprachiasmatic nucleus (SCN), hei utu mo te here ki nga kaiwhakawhiwhi GABAA, penei me nga raau taero penei i te zolpidem.Heoi ano te ahua kaore i te tere te tiimata o te moe, te nui ranei o te moe a te tangata.Ka whakaaetia e te US Food and Drug Administration (FDA) mo te wa roa.Kaore a Ramelteon e whakaatu i tetahi herenga nui ki nga kaiwhakawhiwhi GABAA, e pa ana ki nga paanga anxiolytic, myorelaxant, me te amnesic.Kaore i te rite ki te nuinga o nga maimoatanga o te ohoroa e aro ana ki te GABA (g-aminobutyric acid) matatini receptor, ko te ramelteon he agonist o te kaiwhakawhiwhi melatonin.Ina koa, he nui te kowhiringa mo nga momo iti MT1 me MT2, kua uru ki te pupuri i nga riipene circadian, i runga i te kaiwhakawhiwhi MT3 te kawenga mo etahi atu mahi melatonin.Ka whakamahia ano te 2,3-Dihydrobenzofuran i roto i te whakahiato o nga kaihoko antitumor benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, etc.
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