2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Takawaenga COVID-19

Whakaahuatanga Poto:

Ingoa: 2,3,5-Tri-O-benzyl-D-ribonolactone

Nga kupu taurite: 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone

CAS: 55094-52-5

Te ahua: Ma ki te paura tata ma

Maamaa: ≥99.0%

Takawaenga o Remdesivir (CAS 1809249-37-3) COVID-19

Kounga Teitei, Hanganga Aromoni

Inquiry: alvin@ruifuchem.com


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Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ngā Āhuatanga matū:

Ingoa matū 2,3,5-Tri-O-benzyl-D-ribonolactone
Nga kupu taurite 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir Intermediate
Tau CAS 55094-52-5
Tau CAT RF-PI301
Tūnga Taonga Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi C26H26O5
Taumaha rāpoi 418.49
Iwi Whakarewa 54.0-55.0 ℃
Tikanga Rokiroki Te Pawera o te rūma
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua He kowhai, he ma ranei
Wairewa Wairewa i roto i te CH2Cl2 me te Insoluble i H2O
NMR me MS Me Whakaae
Tautuhinga IR me TLC
makuku ≤1.0%
Te toenga i runga i te mura ≤0.50%
Te poke takitahi ≤0.50%
Nga Korewa Taamaha ≤50ppm
HPLC (210nm) ≥99.0%
HPLC (ELSD) ≥99.0%
Paerewa Whakamatau Paerewa hinonga
Whakamahinga Takawaenga o Remdesivir (CAS 1809249-37-3)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

Painga:

1

FAQ:

Taupānga:

Ko te 2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) he takawaenga Remdesivir.Ko te Remdesivir (CAS 1809249-37-3) he rongoa antiviral hou i roto i te karaehe o nga tairitenga nucleotide, e whakamahia ana hei rongoa i te COVID-19.Ko te Remdesivir (GS-5734) he kupu whakatairite antiviral nucleoside e aukati ana i te huaketo murine hepatitis (MHV) me te EC50 rite ki te SARS-CoV me te MERS-CoV.Ko nga Coronaviruses (CoVs) he huaketo RNA-a-waa-kotahi, ka pangia e te tini o nga kaihautu kararehe.I roto i te tangata, i mohiohia ko nga CoVs te nuinga o te mate maeke me te pneumonia tae noa ki te putanga mai o te coronavirus mate manawa whakapeka kino (SARS-CoV) i te tau 2002 me te Middle East respiratory syndrome coronavirus (MERS-CoV) i te tau 2012 mai i nga punaha zoonotic.Ko Remdesivir te monophosphoramidate prodrug o te C-adenosine nucleoside analogue GS-441524.I roto i nga pūtau pukupuku roro (DBT) kua pangia e te MHV, ka kaha ake te aukati a GS-5734 i te MHV i te GS-441524, me te GS-5734 EC50 o 0.03 M. I tua atu, i whakatauhia nga uara EC50 i muri i te maimoatanga me te GS-441573 me te GS-441524. i roto i te SARS-CoV- me te MERS-CoV i pangia e nga ahurea tuatahi o te tangata epithelial cell (HAE).

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