(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Darunavir Intermediate High Purity
Kaihanga Kaihanga Darunavir Hua e Pa ana:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
Ingoa matū | (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane |
Nga kupu taurite | (2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane;(2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane;Darunavir Intermediate |
Tau CAS | 98737-29-2 |
Tau CAT | RF-PI286 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C15H21NO3 |
Taumaha rāpoi | 263.33 |
Wairewa | Karekau ki te wai.Wairewa ki te Methanol, Chloroform |
Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Tioata-White |
Tautuhi (HPLC) | Ko te Tautuhinga ka Whakamanahia e HPLC |
Iwi Whakarewa | 123.0~128.0 ℃ |
makuku (KF) | ≤0.50% |
Te toenga i runga i te mura | ≤0.20% |
Te Maama / Tikanga Tatauria | ≥99.0% (HPLC) |
Chlorohydrin (HPLC) | ≤0.20% |
Chloromethyl Ketone | ≤0.10% |
Ētahi atu poke kotahi | ≤0.20% |
Nga poke katoa | ≤1.0% |
Te poke o Chiral | ≤0.30% |
Nga Korewa Taamaha | ≤20ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
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Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o (2S,3S) -1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS: 98737-29-2) me te kounga teitei , he takawaenga i te nuinga o te wa i roto i te whakahiatotanga o Darunavir (CAS 206361-99-1) me Darunavir Ethanolate (CAS 635728-49-3).
Ko Darunavir (CAS 206361-99-1) he momo hou o te kore peptide anti retroviral protease inhibitors i roto i te rongoa AIDS.I whakawhanakehia tuatahi e te peka ho'oraa a Johnson, Tibotec.Ko te tino pai o te koiora i roto i nga aukati protease 6 (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir me ABT378/r).Ka mahi ma te aukati i te hanganga o nga matūriki huaketo hou me te pakeke mai i te mata o nga pūtau kaihautu kua pangia me te aukati i te porotease o te huaketo.Ka whakamahia te hua mo te wa roa, ka taea e ia te whakaheke i te mate huaketo HIV i roto i te toto, te whakanui ake i te tatau o nga pūtau CD4, te whakaheke i te tupono o te mate HIV, te whakapai ake i te kounga o te ora me te roa o te ora.He pai mo nga pakeke kua pangia e te mate HIV engari karekau he painga ki te whakamahi i nga raau taero antiretroviral.Me whakakotahi te rongoa me te whakamahi i nga pota iti o te ritonavir me etahi atu raau taero antiretroviral, kia pai ake ai te whai hua.