3-Ethynylaniline CAS 54060-30-9 Purity >99.0% (GC) Erlotinib Hydrochloride Intermediate
Kaihanga rangatira me te kaiwhakarato o Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
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Ingoa matū | 3-Ethynylaniline |
Nga kupu taurite | 3-Aminophenylacetylene |
Tau CAS | 54060-30-9 |
Tau CAT | RF-PI2241 |
Tūnga Taonga | I roto i te Raarangi, Te Whakaputa Whakanui 50MT / Marama |
Tātai rāpoi | C8H7N |
Taumaha rāpoi | 117.15 |
Tairongo | Te Hau, Te Maama |
Kohuatanga | 120 ℃/20 mmHg |
Wairewa wai | Karekau ki te wai |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Kowhai Maama ki te Wai Paraone |
Te Maama / Tikanga Tatauria | >99.0% (GC) |
Wai na Karl Fischer | <0.50% |
Te toenga i runga i te mura | <0.20% |
Nga poke katoa | <1.00% |
Tatamaha Tau (20/20 ℃) | 1.041~1.048 |
Taupū Refactive n20/D | 1.614~1.6195 |
Spectrum Infrared | He rite ki te Hanganga |
Proton NMR Spectrum | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga Rongoa;Erlotinib Hydrochloride Intermediate |
Mōkī: Pounamu Fluorinated, 25kg / Drum, kia rite ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te 3-Ethynylaniline, e mohiotia ana ko 3-Aminophenylacetylene (CAS: 54060-30-9) ka whakamahia hei takawaenga rongoa.Ko te 3-Ethynylaniline he takawaenga o Erlotinib Hydrochloride (CAS: 183319-69-9).Ko te Erlotinib Hydrochloride he iti ngota ngota tyrosine kinase aukati e mahi whakamuri ana i runga i nga kaiwhakawhiwhi tipu epidermal, he hydrochloride o te erlotinib, he rongoa molecular-targeted.Kua whakaaetia e te US Food and Drug Administration (FDA) te erlotinib (Tarceva) me te gemcitabine hei rongoa tuatahi mo te mate pukupuku pancreatic matatau me te metastatic.Ko te nuinga ka whakamahia hei maimoatanga tuarua, tuatoru ranei mo te mate pukupuku o te puku o te rohe, metstatic kore-iti ranei mo te mate pukupuku puku (NSCLC) me te rongoa mo te mate pukupuku pancreatic.Ka whakamahia hei aukati tyrosine mo te maimoatanga NSCLC.Erlotinib Hydrochloride, he quinazoline i ahu mai i te aukati ngota ngota iti o te kinase tipu epidermal growth receptor (EDGFR) tyrosine kinase, i whakaaetia i te Whiringa-a-rangi, 2004, mo te maimoatanga o te mate pukupuku o te huhu kore-iti.