4- [(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Purity >99.0% (HPLC) Almotriptan Aniline Precursor Factory
Ruifu Chemical Supply Almotriptan Malate Intermediates:
Almotriptan Malate CAS 181183-52-8
1-((4-Hydrazinylbenzyl)sulfonyl)pyrrolidine Hydrochloride CAS 334981-11-2
4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1
1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0
4-Chlorobutyraldehyde Diethyl Acetal CAS 6139-83-9
Ingoa matū | 4- [(1-Pyrrolidinylsulfonyl)methyl]aniline |
Nga kupu taurite | 1-[(4-Aminobenzyl)sulfonyl]pyrrolidine;Almotriptan Aniline Precursor |
Tau CAS | 334981-10-1 |
Tau CAT | RF-PI1948 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C11H16N2O2S |
Taumaha rāpoi | 240.32 |
Te Whakarewa | 170.0 ki te 176.0 ℃ |
Kiato | 1.31 |
Wairewa | He iti te wairewa ki Toluene |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Kowhai Kowhai Kowhai Paura |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Ngaronga i te whakamaroke | <0.50% |
Te toenga i runga i te mura | <0.50% |
Max Single poke | <0.50% |
Nga poke katoa | <1.00% |
Nga Korewa Taamaha | <20ppm |
Spectrum Infrared | He rite ki te Hanganga |
NMR | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Almotriptan Aniline Precursor |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
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4- [(1-Pyrrolidinylsulfonyl)methyl]aniline (CAS: 334981-10-1) he takawaenga i roto i te whakarite o Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Precursor.Ko te Almotriptan Malate he momo tarukino triptan ka taea te whakamahi mo te maimoatanga o te mamae o te migraine.Ko te Almotriptan kei roto i te waahanga rongoa o nga agonists kaikawe rerotonin whiriwhiri.Ko te Almotriptan he hononga teitei me te motuhake mo nga kaiwhakawhiwhi serotonin 5-HT, ka arahi atu ki te vascoconstriction o te oko toto roro me te pa ki te tohatoha o te rere toto.Ko enei paanga ka aukati i te tuku tohu mamae ki te roro, me te peehi tonu i te tukunga o etahi matū taiao e puta ai te mamae, te nausea me etahi atu tohu o te migraine.Heoi, kaore a Almotriptan e aukati i nga whakaeke o te heke.Ko Almotriptan, i hokohoko i te tau 2000, kei a ia te teitei o te oralbioavailability i waenga i nga triptans katoa.Ko te Almotriptan ka whakakorikorihia e te MAO-A me te CYP3A4, na reira he pai ake te ahua o nga paanga ki te whakataurite ki te Sumatriptan.