4-(4-Pyridinyl)thiazole-2-thiol CAS 77168-63-9 Purity ≥99.0% Ceftaroline Fosamil Cephalosporin Intermediate
Kaihanga Kaihanga, Te Maamaa Teitei, Te Hanga Aromoni
Ingoa matū: 4-(4-Pyridinyl)thiazole-2-thiol
CAS: 77168-63-9
Ingoa matū | 4-(4-Pyridinyl)thiazole-2-thiol |
Tau CAS | 77168-63-9 |
Tau CAT | RF-PI558 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C8H6N2S2 |
Taumaha rāpoi | 194.28 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura-White ki te Kowhai Kowhai Paura |
Te whakamatautau | ≥99.0% |
Ngaronga i te whakamaroke | ≤0.50% |
Nga Taonga Paanga | |
Takitahi Max.poke | ≤0.50% |
Nga poke katoa | ≤1.0% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Ceftaroline Fosamil (TAK-599), he huanga Cephalosporin |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
Ko te 4-(4-Pyridinyl)thiazole-2-thiol (CAS: 77168-63-9) ka whakamahia hei takawaenga o Ceftaroline Fosamil (TAK-599).Ko te Ceftaroline Fosamil he kaihoko antibacterial cephalosporin i whakaaetia i roto i te United States i Oketopa 2010 mo te maimoatanga IV o te kiri huakita whakapeka me nga mate hanganga kiri (ABSSSI) me te pneumonia huakita kua riro mai i te hapori (CABP).Ko te Ceftaroline Fosamil te wai-wairewa, N-phosphono prodrug o ceftaroline (T-91825), he whanui whanui, he kaihoko huakita me te mahi kaha ki nga riaka Staphylococcus aureus (MRSA) methicillin-resistant, multidrug resistant S. pneumonia, me te karamu noa. -raiao kino.Ka herea te Ceftaroline ki te PBP2a me etahi atu PBP me te tino hononga, a, na te mea, ka mau tonu te mahi kaha.Ko te Ceftaroline e whakaatu ana i te mahi ki te nuinga o nga tukumate karamu-pai, tae atu ki te β-lactam-susceptible and -resistant S. aureus, vancomycin-resistant S. aureus, me nga momo aukati me te whakaraerae o S. pneumoniae engari he ngoikore te mahi ki a Enterococcus sp.Ko te mahi antibacterial karamu-kino o te ceftaroline he iti te nuinga ki nga tukumate manawa penei i te Moraxella catarrhalis me te Haemophilus influenzae.