4-Benzyl-2-Hydroxymorpholin-3-one CAS 287930-73-8 Purity >99.0% (HPLC) Aprepitant Intermediate Factory
Kaihanga rangatira me te kaiwhakarato
Takawaenga o Aprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-one CAS 287930-73-8
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2
Please contact: alvin@ruifuchem.com
| Ingoa matū | 4-Benzyl-2-Hydroxymorpholin-3-one |
| Nga kupu taurite | 4-Benzyl-2-Hydroxy-Morpholin-3-one;2-Hydroxy-4-(Phenylmethyl)-3-Morpholinone;Aprepitant poke 48;Fosaprepitant poke 23;Aprepitant Intermediate Ⅱ |
| Tau CAS | 287930-73-8 |
| Tau CAT | RF2660 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C11H13NO3 |
| Taumaha rāpoi | 207.23 |
| Iwi Whakarewa | 134.0 ki te 138.0 ℃ |
| Kohuatanga | 441.7±45.0℃ |
| Kiato | 1.292±0.06 g/cm3 |
| Wairewa i te wai | DMSO (Paku), Methanol (Paku, Wehana) |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Ma ki te Paura Kiriata-White |
| Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
| Iwi Whakarewa | 134.0 ki te 138.0 ℃ |
| Wai (na Karl Fischer) | <0.50% |
| Te toenga i runga i te mura | <0.20% |
| Nga poke katoa | <1.00% |
| Proton NMR Spectrum | He rite ki te Hanganga |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Takawaenga o te Aprepitant (CAS: 170729-80-3) Taakaro Antiemetic |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
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Ko te 4-Benzyl-2-Hydroxymorpholin-3-one (CAS: 287930-73-8), he takawaenga o Aprepitant (CAS: 170729-80-3), i whakamahia hei raau taero antiemetic.Ko te Aprepitant he kaitukino neurokinin-1 (NK-1) kaiawhina, a no nga rongoa rongoa o te ruaki i te wa o te chemotherapy o te mate pukupuku.I angitu te hanga tuatahi e Merck Company (Tiamana).I te Maehe 2003, i whakaaetia e te US Food and Drug Administration mo te whakamahi mo te maimoatanga o te ruaki chemotherapy.Ko tenei hua he tino hononga ki te tangata i te mea he iti te hononga ki te serotonin, dopamine me te whakahiato glucocorticoid.Ko te Aprepitant, ka honoa ki nga kaitautoko 5-HT3 (penei i te ondansetron hydrochloride) me te corticosteroid dexamethasone, ka taea te whakaiti ake i te cisplatin-induced acute me (ranei) te roa o te emesis.Ko te tono i tenei tarukino anake ka whai hua aukati.
![(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 127852-28-2 Purity >99.0% (GC) Aprepitant Intermediate](https://www.ruifuchemical.com/uploads/R-1-35-Bistrifluoromethylphenylethanol-CAS-127852-28-2-300x300.jpg)