4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Purity >98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory

Whakaahuatanga Poto:

Ingoa: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

CAS: 417721-36-9

Maamaa: >98.5% (HPLC)

Te ahua: Paura-White ki te Paura Kowhai Maama

Takawaenga o Lenvatinib Mesylate CAS 857890-39-2

Kounga Teitei, Hanganga Aromoni

E-Mail: alvin@ruifuchem.com

Tukuna he imeera ki a matou

Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates With High Pure
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Nga Ahuatanga matū:

Ingoa matū	4-Chloro-7-Methoxyquinoline-6-Carboxamide
Nga kupu taurite	4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Lenvatinib poke 12;Lenvatinib poke B;Lenvatinib poke LFS-B
Tau CAS	417721-36-9
Tau CAT	RF-PI1971
Tūnga Taonga	I roto i te Raarangi, Te Whakaputa Whakanui 50MT / Tau
Tātai rāpoi	C11H9ClN2O2
Taumaha rāpoi	236.65
Te Whakarewa	>205℃ (tikuri)
Kiato	1.380±0.060 g/cm3
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Paura-White ki te Paura Kowhai Maama
Te Maama / Tikanga Tatauria	>98.5% (HPLC)
Ngaronga i te whakamaroke	<0.50%
Te toenga i runga i te mura	<0.50%
Nga poke katoa	<1.50%
Proton NMR Spectrum	He rite ki te Hanganga
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga o Lenvatinib Mesylate (CAS: 857890-39-2)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

Painga:

FAQ:

Taupānga:

Ko te 4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) te nuinga o te whakamahi hei takawaenga o Lenvatinib Mesylate (CAS: 857890-39-2).I whakawhanakehia e Eisai Inc., ko te lenvatinib mesylate he aukati vascular endothelial growth factor receptor (VEGF) he mahi ki te VEGF subtypes 1, 2, me 3 a i whakaaetia e te FDA i te tau 2015 mo te maimoatanga o te mate pukupuku thyroid rerekee kei te rohe. he auau, he metastatic, he ahu whakamua ranei, kaore i aro ki te maimoatanga iodine radioactive.I te marama o Haratua 2016, i whakaaetia e te FDA te rongoa hei rongoa whakakotahi me te everolimus mo te maimoatanga o te mate pukupuku o te pukupuku renal.Na te mea ko te VEGF (me nga kaiwhakawhiwhi take tipu fibroblast, e mohiotia ana ko FGFRs) e whakaarohia ana ka whai waahi ki nga huarahi tohu tohu cardiovascular, ko te VEGF2R me te aukati FGFR te whakaaro ko nga tikanga kei muri i te paanga tuatahi o te lenvatinib mesylate, ko te whakaheke toto.