5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Intermediate Factory
Kaihanga Kaihanga, Te Maamaa Teitei, Te Hanga Aromoni
Dapagliflozin (CAS: 461432-26-8) Takawaenga Paanga:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Ingoa matū | 5-Bromo-2-Chlorobenzoic Acid |
| Nga kupu taurite | 2-Chloro-5-Bromobenzoic Acid |
| Tau CAS | 21739-92-4 |
| Tau CAT | RF-PI439 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C7H4BrClO2 |
| Taumaha rāpoi | 235.46 |
| Te Whakarewa | 154.0 ki te 156.0 ℃ (marama) |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Paura-White ki te Paura Kowhai Maama |
| Te whakamatautau | ≥99.0% |
| Wai (KF) | ≤0.50% |
| Te toenga i runga i te mura | ≤0.30% |
| 2-Chlorobenzoic Waikawa | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Nga poke katoa | ≤1.0% |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Takawaenga o Dapagliflozin (CAS: 461432-26-8), momo II mate huka |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
Ko te 5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) ka whakamahia hei mea timatanga i roto i te whakahiatotanga o Dapagliflozin (CAS: 461432-26-8), he konutai-glucose cotransporter-2 aukati e whakaiti ana i nga whatukuhu. te reabsorption glucose me te whakamahia ki te rongoa i nga turoro me te mate huka momo II.Ko te Dapagliflozin he aukati SGLT-2(SLC5A2) kaha me te whiriwhiri me te EC50 o 1.1 nM.He pai te uruhanga puta noa i nga kiriuhi pūtau Caco-2, he taputapu mo te P-glycoprotein (P-gp).I whakaaetia a Dapagliflozin i te 2012 e FDA.
