5-Bromo-2-Chloropyrimidine CAS 32779-36-5 Purity ≥99.5% (HPLC) Macitentan Intermediate Factory
Kaihanga Kaihanga Hokohoko Macitentan Related Intermediates
5-(4-Bromophenyl)-4,6-Dichloropyrimidine CAS 146533-41-7
5-Bromo-2-Chloropyrimidine CAS 32779-36-5
Ingoa matū | 5-Bromo-2-Chloropyrimidine |
Nga kupu taurite | 2-Chloro-5-Bromopyrimidine;Macitentan Intermediate 5 |
Tau CAS | 32779-36-5 |
Tau CAT | RF-PI854 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C4H2BrClN2 |
Taumaha rāpoi | 193.43 |
Te Whakarewa | 73.0~79.0℃ (marama) |
Kohuatanga | 95 ℃/15 mmHg |
Wairewa | Wairewa ki Methanol;Kore ki te wai |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura-White |
Tautuhinga | IR/HPLC |
Te Maama / Tikanga Tatauria | ≥99.5% (HPLC) |
makuku (KF) | ≤0.50% |
Te toenga i runga i te mura | ≤0.20% |
Te poke kotahi | ≤0.30% |
Nga poke katoa | ≤0.50% |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga Rongoa;Macitentan Intermediate |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
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Ko te 5-Bromo-2-Chloropyrimidine (CAS: 32779-36-5) ka whakamahia hei takawaenga rongoa, i roto i te whakahiato o Active Pharmaceutical Ingredients (APIs).Ka whakamahia ano hoki i roto i nga tauhohenga honohono o te indium organometallics me te 2,5-Dihalopyrimidines.Ko te 5-Bromo-2-Chloropyrimidine te takawaenga o Macitentan (CAS: 441798-33-0).I whiwhi a Macitentan i te whakaaetanga a te US FDA i te Oketopa 2013 mo te maimoatanga o te pulmonary arterial hypertension (PAH) (WHO group I) ki te whakaroa i te ahunga whakamua o te mate.