6-Amino-5-Bromoquinoxaline CAS 50358-63-9 Purity >99.0% (HPLC) Brimonidine Tartrate Intermediate

Whakaahuatanga Poto:

Ingoa matū: 6-Amino-5-Bromoquinoxaline

Nga kupu taurite: 5-Bromoquinoxalin-6-Amine

CAS: 50358-63-9

Maamaa: >99.0% (HPLC)

Te ahua: Paura paraone ki te Maama-Kowhai

Takawaenga o Brimonidine Tartrate (CAS: 70359-46-5)

Whakapā: Takuta Alvin Huang

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E-Mail: alvin@ruifuchem.com


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Whakaahuatanga:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Ngā Āhuatanga matū:

Ingoa matū 6-Amino-5-Bromoquinoxaline
Nga kupu taurite 5-Bromoquinoxalin-6-Amine;5-Bromo-6-Quinoxalinamine;5-Bromo-6-Aminoquinoxaline
poke Brimonidine EP Whakakore B
Tau CAS 50358-63-9
Tau CAT RF2515
Tūnga Taonga I roto i te Stock, Production Raukaha 35 Tons ia Marama
Tātai rāpoi C8H6BrN3
Taumaha rāpoi 224.06
Iwi Whakarewa 153.0 ki te 157.0 ℃
Kiato 1.744±0.06 g/cm3
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua Paraone ki te Paura Maama-Kowhai
Te Maama / Tikanga Tatauria >99.0% (HPLC)
Iwi Whakarewa 153.0~157.0℃
Ngaronga i te whakamaroke <1.00%
Max.Te poke takitahi <0.50%
Nga poke katoa <1.00%
Spectrum Infrared He rite ki te Hanganga
Proton NMR Spectrum He rite ki te Hanganga
Paerewa Whakamatau Paerewa hinonga
Whakamahinga Takawaenga o Brimonidine Tartrate (CAS: 70359-46-5)

Iwi Whakarewa
Whakamahia te tikanga whakamatautau whanui me te whakanui ake i te pāmahana 1.5 ℃ / meneti.Me rewa i waenga i te 153.0~157.0 ℃
Ngaronga i te whakamaroke
Kaua e neke ake i te 1.0% Ka whakatauhia ki te 1.0g ma te whakamaroke i roto i te oumu i te 105 ℃ tae noa ki te taumaha tonu
Pūhui pātahi (HPLC)
Pūnaha Chromatographic:
Tīwae: ODS, C18,
Te roangaru kaitirotiro: 264nm
Rere rere: 1.0 ml ia meneti
Wāhanga pūkoro:
Whakapaia he ranunga kua tātarihia, kua whakakorehia hoki o te parepare ( whakakorehia te 2.6g Sodium 1-heptanesulfonate ki te 690ml wai) -methanol-glacial acetic acid-triethylamine (690:310:7.5:2.5) .
Te whakarite otinga tauira:
Wewetehia he tauira 25.0mg tika te pauna i roto i te 25ml wahanga pūkoro.
Tikanga:
Werohia te rōrahi o te 10 l o te otinga tauira ka tuhia nga chromatograms ki te 4 nga wa o te wa pupuri o te tihi matua.Tātaihia ngā tihi poke whakaitihia te tihi pātea.Te tapeke
poke kaua e neke ake i te 1.00%, tetahi poke takitahi kaua e neke ake i te 0.50%.

Te Ara Whakatairanga o 6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9)

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Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

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Whakapumau: Kia mau tonu nga taonga e tika ana

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Ratonga Hangarau Ritenga: Mai i te karamu ki te kirokaramu

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Taupānga:

Ko te 6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9) he takawaenga nui o nga hua o te quinoxaline.Ka whakamahia te 6-Amino-5-Bromoquinoxaline hei takawaenga rongoa, he takawaenga o Brimonidine Tartrate (CAS: 70359-46-5).Ko te Brimonidine he tino whiriwhiringa α2-receptor blocker, i pai te whakawhanake e te US Company Allergan, he rongoa kanohi.Ka taea te whakaheke i te pehanga intraocular (IOP).Ko te Brimonidine Tartrate ophthalmic solution saling i roto i te maakete ko te brimonidine tartrate te ahua, he rongoa pai te whakaheke IOP mo te glaucoma koki tuwhera maataki me te maimoatanga whakaheke toto o nga turoro, engari mo nga taumata IOP taiaho argon.Ko te otinga ophthalmic Brimonidine Tartrate he tikanga mahi takirua ma te whakaheke i te hanga whakakatakata wai me te whakanui ake i te paparanga poaka o nga kaupapa rongoa rerenga scleral wai.I muri i te taka ki roto i te kanohi, ka tere te paanga, ka tae ki te tihi ka whakamahi ki te 2h, ka taea e te wa whai hua te pupuri i te 12h.Ka kitea noa e te toto nga tohu o nga raau taero.Ko tenei hua ka puta tuatahi i roto i te ate, me nga metabolites ka tukuna ki roto i te mimi e nga whatukuhu.Ko te whakauru me te tohatoha o te punaha kaore e pa ana, kaore nga taangata e hiahia ki te whakarereke i te horopeta.Ko te otinga ophthalmic Brimonidine Tartrate ka whakatauritea ki etahi atu α-blockers, he iti te ngako-wairewa, ahakoa kaore i te ngawari ki te haere i roto i te arai toto-roro me te kore e whakaputa i te whakamaarama, te hypotension me etahi atu tauhohenga kino o te pokapū o te clonidine.

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