6-Amino-5-Bromoquinoxaline CAS 50358-63-9 Purity >99.0% (HPLC) Brimonidine Tartrate Intermediate
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Ingoa matū | 6-Amino-5-Bromoquinoxaline |
Nga kupu taurite | 5-Bromoquinoxalin-6-Amine;5-Bromo-6-Quinoxalinamine;5-Bromo-6-Aminoquinoxaline |
poke | Brimonidine EP Whakakore B |
Tau CAS | 50358-63-9 |
Tau CAT | RF2515 |
Tūnga Taonga | I roto i te Stock, Production Raukaha 35 Tons ia Marama |
Tātai rāpoi | C8H6BrN3 |
Taumaha rāpoi | 224.06 |
Iwi Whakarewa | 153.0 ki te 157.0 ℃ |
Kiato | 1.744±0.06 g/cm3 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paraone ki te Paura Maama-Kowhai |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Iwi Whakarewa | 153.0~157.0℃ |
Ngaronga i te whakamaroke | <1.00% |
Max.Te poke takitahi | <0.50% |
Nga poke katoa | <1.00% |
Spectrum Infrared | He rite ki te Hanganga |
Proton NMR Spectrum | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Brimonidine Tartrate (CAS: 70359-46-5) |
Iwi Whakarewa
Whakamahia te tikanga whakamatautau whanui me te whakanui ake i te pāmahana 1.5 ℃ / meneti.Me rewa i waenga i te 153.0~157.0 ℃
Ngaronga i te whakamaroke
Kaua e neke ake i te 1.0% Ka whakatauhia ki te 1.0g ma te whakamaroke i roto i te oumu i te 105 ℃ tae noa ki te taumaha tonu
Pūhui pātahi (HPLC)
Pūnaha Chromatographic:
Tīwae: ODS, C18,
Te roangaru kaitirotiro: 264nm
Rere rere: 1.0 ml ia meneti
Wāhanga pūkoro:
Whakapaia he ranunga kua tātarihia, kua whakakorehia hoki o te parepare ( whakakorehia te 2.6g Sodium 1-heptanesulfonate ki te 690ml wai) -methanol-glacial acetic acid-triethylamine (690:310:7.5:2.5) .
Te whakarite otinga tauira:
Wewetehia he tauira 25.0mg tika te pauna i roto i te 25ml wahanga pūkoro.
Tikanga:
Werohia te rōrahi o te 10 l o te otinga tauira ka tuhia nga chromatograms ki te 4 nga wa o te wa pupuri o te tihi matua.Tātaihia ngā tihi poke whakaitihia te tihi pātea.Te tapeke
poke kaua e neke ake i te 1.00%, tetahi poke takitahi kaua e neke ake i te 0.50%.
Te Ara Whakatairanga o 6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9)
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Me pehea te hoko?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
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Ko te 6-Amino-5-Bromoquinoxaline (CAS: 50358-63-9) he takawaenga nui o nga hua o te quinoxaline.Ka whakamahia te 6-Amino-5-Bromoquinoxaline hei takawaenga rongoa, he takawaenga o Brimonidine Tartrate (CAS: 70359-46-5).Ko te Brimonidine he tino whiriwhiringa α2-receptor blocker, i pai te whakawhanake e te US Company Allergan, he rongoa kanohi.Ka taea te whakaheke i te pehanga intraocular (IOP).Ko te Brimonidine Tartrate ophthalmic solution saling i roto i te maakete ko te brimonidine tartrate te ahua, he rongoa pai te whakaheke IOP mo te glaucoma koki tuwhera maataki me te maimoatanga whakaheke toto o nga turoro, engari mo nga taumata IOP taiaho argon.Ko te otinga ophthalmic Brimonidine Tartrate he tikanga mahi takirua ma te whakaheke i te hanga whakakatakata wai me te whakanui ake i te paparanga poaka o nga kaupapa rongoa rerenga scleral wai.I muri i te taka ki roto i te kanohi, ka tere te paanga, ka tae ki te tihi ka whakamahi ki te 2h, ka taea e te wa whai hua te pupuri i te 12h.Ka kitea noa e te toto nga tohu o nga raau taero.Ko tenei hua ka puta tuatahi i roto i te ate, me nga metabolites ka tukuna ki roto i te mimi e nga whatukuhu.Ko te whakauru me te tohatoha o te punaha kaore e pa ana, kaore nga taangata e hiahia ki te whakarereke i te horopeta.Ko te otinga ophthalmic Brimonidine Tartrate ka whakatauritea ki etahi atu α-blockers, he iti te ngako-wairewa, ahakoa kaore i te ngawari ki te haere i roto i te arai toto-roro me te kore e whakaputa i te whakamaarama, te hypotension me etahi atu tauhohenga kino o te pokapū o te clonidine.