7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Waenga Maama Teitei
Kaihanga Kaihanga Irinotecan me nga Takawaenga Paanga:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Ingoa matū | 7-Ethyl-10-Hydroxycamptothecin |
| Nga kupu taurite | SN-38 |
| Tau CAS | 86639-52-3 |
| Tau CAT | RF-PI242 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C22H20N2O5 |
| Taumaha rāpoi | 392.41 |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Kowhai Maama Tioata Maama Paura |
| Tautuhi (IR, UV) | (1) Ko te tuāwhiorangi whakauru hihi Ultraviolet e rite ana ki nga hiahia (2) Ko te tuāwhiorangi whakauru hihi infrared e rite ana ki te awhi paerewa tohutoro me ū ki nga whakamatautau kua whakaaetia. |
| Te Whakarewa | 228.0~235.0 ℃ |
| Nga Taonga Paanga | ≤1.5% |
| 10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| Mōrahi Te poke kore mohiotia | ≤0.50% |
| Ngaronga i te whakamaroke | ≤1.0% |
| Nga Korewa Taamaha | ≤10ppm |
| Te toenga i runga i te mura | ≤0.10% |
| Maramatanga o te Otinga | Maamaa |
| Te whakamatautau | ≥98.0% (HPLC) |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | Takawaenga Rongoa o Irinotecan |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) me te kounga teitei.Ko te 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) he metabolite kaha o te aukati Topoisomerase I Irinotecan.Ko te SN-38 (NK012) te aukati i te whakahiatotanga o te DNA me te RNA me te IC50s o 0.077 me 1.3 μM, ia.Ko te 7-Ethyl-10-Hydroxycamptothecin (SN-38), ko te metabolite kaha o Irinotecan, he huanga semisynthetic o te camptothecin, he pāhare e pa ana ki te quinoline i kitea i te kiri o te rakau camptotheca Hainamana me te rakau nothapodytes Ahia.Ahakoa ko te 7-Ethyl-10-Hydroxycamptothecin ki te 1,000 te kaha ake i te Irinotecan, kaore i hurihia hei kaitono tarukino whaihua na te mea he koretake.I tenei wa ka tukuna ki nga whakamatautau haumanu me etahi atu waahanga ka taea pea te whai hua hei rongoa antineoplastic.
