Acesulfame K CAS 55589-62-3 Acesulfame Potassium Purity >99.0% (HPLC)

WHAKAMAHI
Ko te Acesulfame Potassium kei roto i te NLT 99.0% me te NMT 101.0% o C4H4NO4SK, kua tatauhia i runga i te whakamaroke.
WHAKATAUTANGA
• A. KAUPAPA INFRARED <197K>
• B. WHAKATAUTANGA WHAKATAUTANGA-WAHAU, Pahaura <191>
Tauira otinga: 100 mg/mL
Paearu whakaae: Ka tutuki nga whakaritenga
WHAKAMAHI
• TE WHAKAMAHI
Tauira: 150 mg
Pūnaha Titrimetric (Tirohia Titrimetry <541>)
Aratau: Te titration tika
Titrant: 0.1 N te waikawa perchloric VS
Patea: 50 mL waikawa ahetiki hukapapa
Te kitenga ira mutunga: Potentiometric
Tātaritanga: Whakarewahia te Tauira ki te 50 mL waikawa ahetiki hukapapa.
Titrate ki te 0.1 N te waikawa perchloric VS.Whakaritehia he whakatau patea.
Tātaihia te ōrau o te pāhare pāporo acesulfame (C4H4NO4SK) i te Tauira:
Hua = [(V − B) × N × F × 100]/W
V = rōrahi titrant i pau i te Tauira (mL)
B = rōrahi titrant i pau i te Patea (mL)
N = te tairitenga orite tonu (mEq/mL)
F = tauwehe taurite, 201.2 mg/mEq
W = te taumaha o te Tauira (mg)
Paearu whakaae: 99.0%–101.0% i runga i te tikanga whakamaroke
NGA POKE
• TE TEITI O TE FLUORIDE
[FAKATOKANGA-Whakamahia nga taputapu kirihou puta noa i tenei whakamatautau.]
Rongoā A: Whakarewahia te 210 g o te waikawa citric monohydrate ki te 400 mL wai.Whakaritea ki te haukinia ki te pH 7.0, ka waimeha ki te wai ki te 1000 mL.
Otinga B: 132 mg/mL o te haukinia phosphate dibasic
Rongoā C: Ki te whakatārewatanga o te 292 g waikawa edetic i roto i te 500 mL o te wai, tāpirihia te 200 mL o te haukinia haukinia, whakatikahia me te haukinia waikawa ki te pH i waenga i te 6 me te 7, ka waimeha ki te wai kia 1000 mL.
Wairewa parepare: Whakaranuhia nga pukapuka rite o te Otinga A, te Otinga B me te Otinga C, me te whakatikatika me te haukinia waiwai ki te pH 7.5.
Te otinga kararehe paerewa: Paunatia te 0.442 g konutai fluoride, i whakamarokehia i mua i te 300° mo te 12 haora, ki roto i te ipu 1-L, ka waimeha ki te wai ki te rōrahi.Whakaorangia te otinga ki roto i te ipu kirihou kati.I mua tonu i te whakamahi, paipa te 5 mL o tenei wairewa ki roto i te ipu 100-mL, ka waimeha ki te wai ki te rōrahi.Kei ia mL o tenei wairewa te 10µg o te katote fluoride.
Wairewa Paerewa A: Whakaranuhia te 0.5 mL o te wairewa kararehe Paerewa me te 15.0 mL o te wairewa Buffer, ka waimeha ki te wai ki te 50mL.
Wairewa Paerewa B: Whakaranuhia te 1.0 mL o te wairewa rakau Paerewa me te 15.0 mL o te wairewa Buffer, ka waimeha ki te wai ki te 50mL.
Wairewa Paerewa C: Whakaranuhia te 1.5 mL o te wairewa kararehe Paerewa me te 15.0 mL o te wairewa Buffer, ka waimeha ki te wai ki te 50mL.
Wairewa Paerewa D: Whakaranuhia te 3.0 mL o te wairewa kararehe Paerewa me te 15.0 mL o te wairewa Buffer, ka waimeha ki te wai ki te 50mL.
Tauira otinga: Ki te 50-mL ipu rōrahi tāpiri 3 g o Acesulfame Potassium.Whakarewa ki te wai, tāpirihia te 15.0 mL o te wairewa Buffer, ka waimeha ki te wai ki te rōrahi.
Tātaritanga
Tauira: Wairewa Paerewa A, otinga Paerewa B, Wairewa Paerewa C, otinga Paerewa D, me te otinga Tauira
Whakatauritea te pumanawa (tirohia te Titrimetry <541>) i roto i te mV, o nga otinga Paerewa me te otinga Tauira, me te mita pH e tika ana kua oti te whakauru ki te hiko hiko-whakaahua me te hiko tohutoro maaota hiriwa-hiriwa.Ina tango i nga inenga, whakawhitia te otinga ki te ipurau 25-mL, ka rukuhia nga hiko.Whakauruhia he pae whakakorikori kua pania ki te polytef ki roto i te ipurau, tuuhia te ipurau ki runga i te whakakorikori aukume me te tihi o runga, ka whakakorikoria kia tae ra ano te taurite (1-2 min).Horoi, ka whakamaroke i nga hiko i waenga i nga inenga, kia tupato kei rauria te karaihe i roto i te hiko katote-a-fluoride.Inehia te kaha o ia wairewa Paerewa, ka tohuhia te kukū o te fluoride, i roto i te µg/mL, ki te pumanawa, i roto i te mV, ki runga pepa semilogarithmic.Ine i te kaha o te Tauira otinga, me te whakatau i te kukū pūkōwhai mai i te ānau paerewa, i roto i te µg/mL.
Tātaihia te ihirangi, i roto i te ppm, o te fluoride i te wahanga o te Acesulfame Potassium i tangohia:
Hua = (V × C/W)
V = rōrahi o te Tauira otinga (mL)
C = te kukū o te pūkōwhai i roto i te Tauira otinga, mai i te ānau paerewa (mg/mL)
W = te taumaha o te Acesulfame Potassium i tangohia hei whakarite i te Tauira otinga (g)
Paearu whakaae: NMT 3 ppm
• NGA METAL TAITAHA, Tikanga I <231>: NMT 10 ppm
• TE PARAU KORERO
Rongoā A: 3.3 mg/mL o te tetrabutylammonium hydrogen sulfate
Wāhanga pūkoro: Acetonitrile me Solution A (2:3)
Te otinga pai o te punaha: 2 µg/mL ia USP Acesulfame Potassium RS me te ethylparaben
Te otinga paerewa: 0.2 µg/mL o USP Acesulfame Potassium RS
Tauira otinga: 10 mg/mL
Pūnaha Chromatographic
(Tirohia te Chromatography <621>, Whakaritenga Pūnaha.)
Aratau: LC
Kaitirotiro: UV 227 nm
Tīwae: 4.6-mm × 25-cm;5-µm tākai L1
Rere rere: 1 mL/min
Rahi werohanga: 20 µL
Te pai o te punaha
Tauira: Te otinga pai o te punaha
Nga whakaritenga e tika ana
Whakatau: NLT 2 i waenga i te pāhare pāporo acesulfame me te ethylparaben
Tātaritanga
Tauira: otinga Paerewa me te otinga Tauira
Tuhia nga chromatograms mo te wa oma NLT kia toru nga wa o te wa pupuri o te tihi konupora acesulfame, me te ine i nga urupare rohe o nga tihi.
Paearu whakaae: Ko te whakautu o tetahi tihi i te wa pupuri i tua atu i te konupora acesulfame mai i te otinga Tauira kaore e nui ake i te whakautu o te tihi konupora acesulfame mai i te otinga Paerewa (0.002%).
NGA WHAKAMATAUTANGA
• TE KAUPAPA, TE KAUPAPA RANEI
Tauira otinga: 4.0 g i roto i te 20 mL o te wai waro haukore-kore
Tātaritanga: Tāpirihia te 0.1 mL o te bromothymol blue TS.Mēnā he kōwhai te wairewa, whakahāwea ki te 0.01 N konutai waihā kia puta he tae kahurangi.Mēnā he kahurangi te wairewa, whakahāwea ki te waikawa pūhaumāota 0.01 N kia puta he tae kōwhai.
Paearu whakaae: NMT 0.2 mL o te 0.01 N te konutai waikawa me te NMT 0.2 mL o te 0.01 N te waikawa hauwai.
• NGARO I TE WHAKAMAROKE <731>: Me whakamaroke he tauira ki te 105° mo te 3 haora: ka ngaro te NMT 1.0% o tona taumaha.
HE WHAKAMAHI ATU
• TE PAKITANGA ME TE WHAKAPUTANGA: Whakaorangia ki roto i te ipu kati pai, ka tiakina mai i te marama.Rokiroki ki te pāmahana rūma.
USP REFERENCE STANDARD <11>
USP Acesulfame Potassium RS