Afatinib Dimaleate Intermediate CAS 314771-88-5 Purity >99.0% (HPLC) Factory

Whakaahuatanga Poto:

Ingoa Matū: (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine

CAS: 314771-88-5

Maamaa: >99.0% (HPLC)

Te ahua: Kowhai ki te Paura Kowhai Maama

Takawaenga o Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

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Whakaahuatanga:

Ruifu Chemical Supply Takawaenga o Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Waikawa Diethylphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-kotahi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Ngā Āhuatanga matū:

Ingoa matū	(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine
Nga kupu taurite	N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Afatinib poke
Tau CAS	314771-88-5
Tau CAT	RF-PI2027
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C18H14ClFN4O4
Taumaha rāpoi	404.78
Kiato	1.534±0.060 g/cm3
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Kowhai ki te Paura Kowhai Maama
Te Maama / Tikanga Tatauria	>99.0% (HPLC)
Ngaronga i te whakamaroke	<0.50%
Te poke takitahi	<0.50%
Nga poke katoa	<1.00%
Nga Korewa Taamaha	≤20ppm
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	Takawaenga o Afatinib Dimaleate (CAS: 850140-73-7)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

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Taupānga:

(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) ka whakamahia i roto i te te whakarite o Afatinib Dimaleate (CAS: 850140-73-7).Ko te Afatinib he rongoa hou mo te mate pukupuku, he reanga hou mo te rongoa waha, te rongoa tuatahi o te ao hei patu i te mate pukupuku e herea ana ki te whanau ErbB, a, he pai ake, he whainga Ka aukati i te tohu e whakaohooho ana i te tipu o nga pūtau mate pukupuku. , te whakaiti, te whakaroa ranei i te tipu o nga pūtau mate pukupuku.No roto a Afatinib i te karaehe o nga raau taero e mohiotia ana ko te aukati tyrosine kinase.Ka mahi ma te aukati i te mahi a nga pūmua e rua e hono tata ana, ko te kaiawhina tupu epidermal growth factor (EGFR) me te tangata epidermal growth factor receptor 2 (HER2).Ka whakamahia mo te maimoatanga raina-tuatahi o nga turoro me te mate pukupuku pukupuku pūtau kore-iti.Ko te Afatinib he rongoa hou mo te mate pukupuku, he reanga hou mo te rongoa waha, te rongoa tuatahi o te ao hei patu i te mate pukupuku e herea ana ki te whanau ErbB, a, he pai ake, he whainga Ka aukati i te tohu e whakaohooho ana i te tipu o nga pūtau mate pukupuku. , te whakaiti, te whakaroa ranei i te tipu o nga pūtau mate pukupuku.