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Ingoa: Anastrozole

CAS: 120511-73-1

Te ahua: Ma ki te Paura Tioataata-Ma

Whakatau: 98.0%~102.0%

AnastrozoleTe maimoatanga mo te mate pukupuku uma

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Ko te Kaihanga Kaihanga me te Maama me te Kounga Pumau
Ingoa matū: Anastrozole
CAS: 120511-73-1

Ngā Āhuatanga matū:

Ingoa	Anastrozole
Nga kupu taurite	Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Tau CAS	120511-73-1
Tau CAT	RF-API74
Tūnga Taonga	Kei roto i nga taonga, ka eke ki te rau kirokaramu
Tātai rāpoi	C17H19N5
Taumaha rāpoi	293.37
Wairewa	Wairewa i roto i te DMSO me te Ethanol
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Ma ki te Paura Tioata-White
Tautuhi A	IR/MS Kia rite ki te paerewa tohutoro
Tautuhinga B	HPLC me te ahua o te tihi: He rite ki te tohutoro
Iwi Whakarewa	81.0~84.0℃
Ihirangi Wai (na KF)	≤0.30%
Te toenga i runga i te mura	≤0.10%
Ngaronga i te whakamaroke	≤0.50%
Nga Korewa Taamaha	≤10ppm
Nga Taonga Paanga
Te poke A	≤0.10%
Te poke B	≤0.20%
Te poke C	≤0.20%
Te poke D	≤0.10%
Te poke E	≤0.10%
Takitahi Ētahi atu poke	≤0.10%
Nga poke katoa	≤0.50%
Wairewa toenga
Cyclohexane	≤0.30%
Ethyl Acetate	≤0.50%
Te whakamatautau	98.0%~102.0% (i runga i te whakamaroke)
Te Ora Papa	24 Marama
Paerewa Whakamatau	Paerewa hinonga;United States Pharmacopoeia (USP) Paerewa
Whakamahinga	Te maimoatanga mo te mate pukupuku uma

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.

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Taupānga:

Ko Anastrozole (CAS 120511-73-1), he kore-steroidal, tuatoru-whakatupuranga achiral triazole pärönaki hokohoko rite ARIMIDEX® e AstraZeneca Pharmaceuticals LP1.Koinei tetahi o te tuatoru-whakatupuranga aromatase inhibitor he tino whakataetae me te whiriwhiri o te aromatase, na reira ka aukati i te huringa o te testosterone ki te estradiol me te androstenedione ki te estrone.Ko te aukati i te whaariki aromatase ka puta ma te whakataetae whakataetae o te aromatase ki te hemegroup o te cytochrome P450, te whakaheke i te koiora o te estrogen i roto i nga kopa peripheral o te tinana me te u.

Ko te Anastrozole he maimoatanga pai mo te mate pukupuku u moata.Pērā i ētehi atu aukati aromatase, ko tōna pānga kino tino nui ko te nui ake o te mōrea o te whatinga o te wheua, mo te anastrozole i herea ki te wa maimoatanga.He ngawari te paitini ina whakaritea ki te chemotherapy;heoi, kua kitehia he maha ake nga turoro e rongoa ana me te anastrozole kua amuamu mo nga tohu hono atu i te mea i tumanakohia, ina koa ko te maro o te mamati he rite ki te mate rūmātiki.Ko etahi o nga whakamatautau haumanu o te anastrozole mo nga wahine kua pahemo me te mate pukupuku uma i Uropi me te United States i kii ko nga raru o te musculoskeletal he raru kino.Ko te Anastrozole (Arimidex®) he aukati aromatase kua whakaaetia i roto i te EU, te US me etahi atu whenua o te ao mo te whakamahi hei maimoatanga awhina i roto i nga wahine kua pahemo me te wa moata, te mate pukupuku o te pukupuku o te homoni.Ka whakaaetia ano i roto i te EU me etahi atu whenua o te ao mo te haere tonu o te maimoatanga awhina i roto i nga wahine kua 2-3 tau te maimoatanga tamoxifen awhina mo te mate pukupuku uma.