Apixaban CAS 503612-47-3 Purity ≥99.5% (HPLC)
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o Apixaban (CAS: 503612-47-3) me te kounga teitei.Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona a Apixaban,Please contact: alvin@ruifuchem.com
| Ingoa matū | Apixaban |
| Nga kupu taurite | 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine -3-carboxamide, 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3, 4-c]pyridine-3-carboxamide, BMS 562247, BMS-562247 |
| Tūnga Taonga | I roto i te Stock, Production Arumoni |
| Tau CAS | 503612-47-3 |
| Tātai rāpoi | C25H25N5O4 |
| Taumaha rāpoi | 459.51 g/mol |
| Iwi Whakarewa | 235.0~238.0℃ |
| Kiato | 1.42 |
| COA & MSDS | Kei te waatea |
| Taketake | Shanghai, Haina |
| Kāwai | API |
| Waitohu | Ruifu Chemical |
| Nga taonga | Nga Paerewa Tirotiro | Hua |
| Te ahua | Ma ki te Paura Tioata-White | Ka tutuki |
| Ngaronga i te whakamaroke | ≤0.50% | 0.10% |
| Te toenga i runga i te mura | ≤0.10% | 0.08% |
| Konga Taamaha (hei Pb) | ≤20ppm | Ka tutuki |
| Nga Taonga Paanga | ||
| Tetahi poke kotahi | ≤0.50% | Ka tutuki |
| Nga poke katoa | ≤0.50% | Ka tutuki |
| Te Maama / Tikanga Tatauria | ≥99.5% (HPLC) | 99.9% |
| Spectrum Infrared | He rite ki te Hanganga | Ka tutuki |
| 1 H NMR Spectrum | He rite ki te Hanganga | Ka tutuki |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga | |
Mōkī:Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke (2~8 ℃) me te hau pai kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.
Tukunga:Tukuna ki te ao ma te rangi, ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Karekau tetahi o nga hua ka tukuna ki nga whenua e taupatupatu ana tenei ki nga patent o naianei.Heoi ko te kawenga whakamutunga kei te kaihoko.
Mo te whakamahi rangahau putaiao anake, kaua mo nga kaupapa arumoni, kaua mo te whakamahi tangata, mo te mahi tātaritanga ranei.
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
Ko Apixaban (CAS: 503612-47-3) he momo hou o te raau taero anticoagulant waha i hangaia e Bristol Myers Squibb me Pfizer.He ahua hou mo te aukati Xa-a-waha, a ko tona ingoa arumoni ko Eliquis.Ka whakamahia a Apixaban ki te rongoa i nga turoro pakeke e mahi ana i nga mahi whakakapi hipoki, turi ranei hei aukati i te thromboembolism (VTE)
Ko te Apixaban (CAS: 503612-47-3) he aukati-a-waha kua whakahohehia te Xa tauwehe ka taea te aukati i te whakatipuranga thrombin me te thrombosis.
Ko Apixaban (CAS: 503612-47-3) te tuatoru o nga anticoagulant waha hou ki te hoko, whai muri i te dabigatran me te rivaroxaban, a kua whakaaetia i Uropi mo te aukati i te thromboembolism venous i roto i nga turoro e whai ana i te pokanga whakakapi hipoki, turi ranei.I roto i enei anticoagulants waha e toru i whakaaetia i Uropi, ka whakatauritea ki te maimoatanga aukati paerewa o naianei mo te thromboembolism venous, te enoxaparin, te rivaroxaban i tino pai i roto i te whakamatautau rekoata, me te pai ake o te apixaban i te whakamatautau o mua.He pai ake nga hua whakaora a Rivaroxaban, engari he nui ake te toto i to te apixaban.I kii nga kairangahau i enei rereketanga ki te wa rongoa, na te mea i tangohia te rivaroxaban i nga haora 6-8 i muri i te pokanga i roto i te whakamatautau rekoata, i whakamahia te apixaban i nga haora 18 i muri i te pokanga i te whakamatautau o mua.Ko enei raau taero he pai ake te rongoa ka whakamahia tata ki te wa o te pokanga, engari ka nui ake te mate toto.I kitea e te rangahau haumanu ka whakatauritea ki te werohanga i raro i te kiri o ia ra o te 40mg enoxaparin, e 2 inenga 2.5mg a-waha o te apixaban he pai ake te aukati i te thromboembolism whai i muri i te pokanga whakakapi hipoki, turi ranei, kaore i piki ake te tupono ki te whakaheke toto.
Ko Apixaban (CAS: 503612-47-3) he momo hou o te aukati Xa-a-waha i hangaia e Bristol-Myers Squibb me Pfizer.Ko te ingoa hokohoko ko te eratol, he momo hou o te rongoa o te waha.Na roto i te aukati i tetahi take nui o te coagulation Xa, ka taea e te apixaban te aukati i te hanga thrombin me te thrombosis.I te Paenga-whāwhā 26, 2007, i hono atu a Bristol-Myers Squibb ki a Pfizer ki te whakapuaki i te mahi tahi ki te whakawhanaketanga o te apixaban anticoagulant waha hou na Bristol-Myers Squibb hei whakakapi mo te warfarin.E ai ki te whakaaetanga mahi tahi, ka utua e Pfizer he utu mo te US $0.25 piriona ki a Bristol-Myers Squibb ki te kawe i te 60% o te katoa o te utu whanaketanga o te anticoagulant apixaban (ka whakatinanahia mai i te Hanuere 1, 2007), ko Bristol-Myers. Ka mau a Squibb i te toenga o te 40%, na reira ka whai mana ki te hanga tahi me te hoko i te tarukino.I te marama o Mei 2011, ko apixaban te tuatahi ki te whakaae ki te aukati i te thrombosis venous i roto i nga turoro pakeke e mahi ana i nga mahi whakakapi hipoki, turi ranei i roto i nga whenua 27 EU, Iceland me Norway.I te Whiringa-a-rangi 20, 2012, i whakaaetia e te Komihana a te Pakeha a Ererto (apixaban) mo te aukati i te whiu me te embolism pūnaha i roto i nga turoro pakeke me te kore-valvular atrial fibrillation (NVAF) me te kotahi, neke atu ranei nga mea morearea.I muri mai, ka whakaaetia e te Canadian Food and Drug Administration, Japan, me te US FDA a Ererto?(apixaban) mo te aukati i te whiu me te embolism pūnaha i roto i nga turoro pakeke me te kore-valvular atrial fibrillation (NVAF) me te kotahi, neke atu ranei nga mea morearea.I te Paenga-whāwhā 12, 2013, ko te rongoa anticoagulant hou Eloto (ELIQUIS)(apixaban) i hangaia tahitia e Bristol-Myers Squibb me Pfizer i panuitia mana kia whakarārangihia ki Haina.Ko Ererto he mea hou mo te aukati Xa-waha mo te aukati i te thromboembolism venous (VTE) i roto i nga turoro pakeke e whai ana i te whakakapi hipoki, turi ranei.Ko tana rarangi ingoa he whiringa hou haumaru me te whai hua mo te haumanu anticoagulation i muri i te pokanga orthopedic, me te kawe korero pai ki nga turoro Hainamana e whai ana i te whakakapi i te hip/turi.Kua whakapumautia e nga rangahau haumanu ka whakaritea ki te 40mg enoxaparin kotahi ia ra, e 2 nga wa ia ra te whakahaere waha o eratol?(apixaban) He pai ake te 2.5mg mo te aukati i te thromboembolism venous i muri i te pokanga whakakapi o te hope, turi ranei, a kaore e nui ake te mate o te toto.Ko te ahua 1 e whakaatu ana i nga papa Elotoapixaban i hangaia e Bristol-Myers Squibb me Pfizer.
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