Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Kaihanga Kaihanga Argatroban Kaiwaenga e Pa ana:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
Ingoa matū | Argatroban |
Nga kupu taurite | Argatroban Anhydrous |
Tau CAS | 74863-84-6 |
Tau CAT | RF-API67 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C23H36N6O5S |
Taumaha rāpoi | 508.63 |
Iwi Whakarewa | 188.0~189.0℃ |
Kohuatanga | 801.3ºC i te 760 mmHg |
Kiato | 1.47 g/cm3 |
Tikanga Tukunga | Ka tukuna i raro i te pāmahana ambient |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Tioata-White |
Tautuhinga HPLC | Ko te wa pupuri o te tihi maataapono i whiwhi mai i te otinga Whakamatau ka rite ki tera i puta mai i te otinga Paerewa, hei whakamatautau i te Assay |
Tautuhinga IR | He rite ki te IR Spectrum o AG RS |
Tautuhi UV | I roto i te 259nm me te 332nm te roangaru wahi me whai morahi absorption |
Wai | 2.5-4.5% |
Tae Otinga me te Maama | Ko te otinga Me Maamaa nga Tae |
Whakawhanaunga matū | |
Te poke A + te poke H | ≤0.10% |
Te poke B | ≤0.10% |
Te poke C + Te poke E | ≤0.10% |
Te poke D | ≤0.10% |
Te poke I | ≤0.10% |
Bach o te poke kore | ≤0.10% |
Nga poke katoa | ≤0.30% |
Wairewa toenga | |
Mewaro | ≤3000ppm |
Ewaro | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl Acetate | ≤5000ppm |
Enantiomer (HPLC) | ≤0.10% |
Isomer Ratio (HPLC) | 30.0%-40.0% |
pūhaumāota | ≤0.01% |
Te toenga i runga i te mura | ≤0.10% |
Nga Korewa Taamaha | ≤10ppm |
Endotoxins huakita | <5EU/mg |
Tepe Microbial | TAMC ≤1000 cfu/g |
Te whakamatautau | 98.0%-102.0% (i runga i te waikore) |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | API, Hangaia Antithrombotic Agent Anticoagulant |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua me te kaiwhakarato o Argatroban (CAS: 74863-84-6) me te kounga teitei, API.
Ko Argatroban (CAS: 74863-84-6) he kaihoko antithrombotic waihanga hou e whai hua ana ki te tiaki anticoagulation ratou ischemic stroke me te tohatoha intravascular coagulation.He anticoagulant he iti ngota ngota aukati thrombin tika.I te tau 2000, i raihanatia a argatroban e te Kai me te Taakaro Whakahaere (FDA) mo te aukati me te maimoatanga o te thrombosis i roto i nga turoro me te heparin-induced thrombocytopenia (HIT).I te tau 2002, i whakaaetia kia whakamahia i roto i nga wawaotanga coronary percutaneous i roto i nga turoro kua HIT, kei te tupono ranei ki te whakawhanake.I roto i te 2012, i whakaaetia e te MHRA i te UK mo te anticoagulation i roto i nga turoro me te heparin-induced thrombocytopenia Type II (HIT) e hiahia ana ki te maimoatanga antithrombotic parenteral.