Aripiprazole CAS 129722-12-9 Purity >99.0% (HPLC) API
Ko nga Kaihanga Kaihanga Kaiwaenga o Aripiprazole me te tino parakore
Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Ingoa matū | Aripiprazole |
| Nga kupu taurite | 7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]butoxy]-3,4-Dihydro-2(1H)-Quinolinone |
| Tau CAS | 129722-12-9 |
| Tau CAT | RF-PI2270 |
| Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
| Tātai rāpoi | C23H27Cl2N3O2 |
| Taumaha rāpoi | 448.39 |
| Wairewa | Kore Wairewa ki te Wai;Kore ki te Methanol |
| Waitohu | Ruifu Chemical |
| Tūemi | Whakatakotoranga |
| Te ahua | Paura ma, tata ma ranei te kirikiriata |
| Tautuhinga | Na IR;Na HPLC |
| Wairewa | Wairewa i roto i te Acetic Acid, Iti Rirewa ki te Ethanol |
| Iwi Whakarewa | 136.0~140.0 ℃ |
| Ngaronga i te whakamaroke | <0.50% |
| Te toenga i runga i te mura | <0.10% |
| Nga Korewa Taamaha | ≤20ppm |
| Wairewa toenga | |
| Ewaro | ≤1000ppm |
| DMF | ≤200ppm |
| Nga Taonga Paanga | |
| Tetahi poke kotahi | <0.20% |
| Nga poke katoa | <1.00% |
| Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
| Te whakamatautau | 98.0%~102.0% (i runga i te Turanga Anhydrous) |
| Nga rohe moroiti | |
| Tatau Moroiti Aerobic Tapeke | ≤1000 cfu/g |
| Whakakotahitia te rewena me te pokepokea ai | ≤100 cfu/g |
| E·Coli | Te korenga |
| Whakaritenga Pathogenic | Te korenga |
| Paerewa Whakamatau | Paerewa hinonga |
| Whakamahinga | API;Antipsychotic |
Mōkī: Pounamu, 5kg / Aluminium tine, 25kg / Cardboard Drum, kia rite ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko te Aripiprazole (CAS: 129722-12-9) he momo hou o te quinoline tino wairewa lipid, ko ona ahuatanga rongoa ko te mea ehara i te mea ko te postsynaptic dopamine D2 antagonist, engari ko te presynaptic dopamine D2 receptor agonist, ka taea hoki. whakaongaonga D1, D3, D4 receptors.Ko te Aripiprazole he reanga tuarua atypical antipsychotic me te anti-depressant me te mahi agonist waahanga i te dopamine D2 me te serotonin 5-HT1A nga kaiwhakawhiwhi me te mahi antagonist i nga kaiwhakawhiwhi serotonin 5-HT2A.Ko nga uara Ki ko 0.34 nM, 0.8 nM, 1.7 nM, me te 3.4 nM, mo te dopamine D2 me D3, serotonin 5-HT1A me 5-HT2A nga kaiwhiwhi.Ka whakamahia te Aripiprazole mo te maimoatanga o te schizophrenia me nga mate hinengaro e pa ana.Ko Bristol-Myers Squibb me Otsuka Pharmaceutical Company i kii kua whakaaetia e te Kotahitanga o Europi a Abilify (Aripiprazole) mo te maimoatanga o te tono rarangi schizophrenia.Ko te Schizophrenia e pa ana ki te 1% o te taupori o te ao, me te maha atu o nga taiohi pakeke.Ka pangia e te Schizophrenia te whakaaro, te mana hinengaro me te kaha ki te whakatau whakatau o te manawanui.Ka whai tohu te hunga mate Schizophrenia-pai penei i te pohehe me te pohehe, ko nga turoro he tohu kino ko te wehe hapori, te kore o nga huringa aronganui.I te tau 2002 i whakaaetia e te FDA a Abilify mo te maimoatanga o te schizophrenia, e rima nga kaha inenga: 5 mg, 10 mg, 15 mg, 20 mg me te 30 mg, mai i tana whakaaetanga.
