Atazanavir CAS 198904-31-3 Purity ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor
Whakarato me te Maama me te Kounga Pumau
Ingoa matū: Atazanavir
CAS: 198904-31-3
HIV-1 Protease Inhibitor
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa matū | Atazanavir |
Nga kupu taurite | BMS-232632 |
Tau CAS | 198904-31-3 |
Tau CAT | RF-API70 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C38H52N6O7 |
Taumaha rāpoi | 704.86 |
Iwi Whakarewa | 207.0~209.0℃ |
Wairewa | Wairewa i roto i te DMSO;Karekau ki te wai |
Rokiroki mo te wa roa | Rokiroki mo te wa roa ki te -20 ℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura ma |
Puka | Turanga Free |
Ngaronga i te whakamaroke | ≤0.50% |
Te toenga i runga i te mura | ≤0.20% |
Nga Korewa Taamaha | ≤20ppm |
Te poke A | ≤0.10% |
Te poke B | ≤0.10% |
Te poke kotahi | ≤0.20% |
Nga poke katoa | ≤1.0% |
Tikanga Maama/Atatari | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | HIV-1 Protease Inhibitor Anti-HIV |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko te Atazanavir (CAS 198904-31-3) he rongoa antiretroviral, pakiwaitara me te rongoa azapeptide kaha o te karaehe aukati protease (PI).Ka hokona i raro i te ingoa hokohoko Reyataz.Ka rite ki etahi atu antiretrovirals, ka whakamahia ki te rongoa i te mate o te tangata mate mate mate momo 1 (HIV-1) protease enzyme me te aukati tonu Ki o 66 nmol/L me te aukati hoki i te tukuruatanga viral o HIV-1 me te 50% te kukū whai hua EC50 mai i 2.6 ki te 5.3 nmol/L.Ka herea e te Atazanavir ki te HIV-1 protease hei aukati i te wehenga o te gag me te gag-pol polyproteins, e hua ai te hanga o nga virion pakeke i roto i nga ruma kua pangia e te HIV-1.He rereke te hanganga matū hangarite C-2 o Atazanavir me te kaha antiretroviral i te nuinga o te waa ki nga momo mate HIV ka whakaritea ki etahi atu aukati protease, tae atu ki te Indinavir, Nelfinavir, Ritonavir, Saquinavir me Amprenavir.He rereke te Atazanavir mai i etahi atu PI na te mea ka taea te hoatu kotahi i ia ra, ka iti ake nga paanga ki te tohu lipid o te manawanui.Pērā i ētahi atu aukati protease, ka whakamahia anake me etahi atu rongoa HIV.Ko te Atazanavir he kaupapa aukati HIV protease hou azapeptide.Antiviral.Ka tangohia e te mangai kotahi i te ra.