Atazanavir Sulfate CAS 229975-97-7 Purity ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor
Whakarato me te Maama me te Kounga Pumau
Ingoa matū: Atazanavir Sulfate
CAS: 229975-97-7
HIV-1 Protease Inhibitor
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa matū | Atazanavir Sulfate |
Nga kupu taurite | BMS-232632 Sulfate |
Tau CAS | 229975-97-7 |
Tau CAT | RF-API71 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C38H52N6O7.H2SO4 |
Taumaha rāpoi | 802.93 |
Iwi Whakarewa | 195.0~198.0℃ |
Wairewa | Karekau ki te wai, ka whakarewahia ki te DMSO |
Rokiroki mo te wa roa | Rokiroki mo te wa roa ki te -20 ℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura Ma, Paura-Ma ranei |
pūkawa | 12.0~12.5% |
Ngaronga i te whakamaroke | ≤0.50% |
Te toenga i runga i te mura | ≤0.10% |
Nga Korewa Taamaha | ≤20ppm |
Te poke kotahi | ≤0.30% |
Nga poke katoa | ≤1.0% |
Tikanga Maama/Atatari | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | HIV-1 Protease Inhibitor Anti-HIV |
Mōkī: Pounamu, Peeke konumohe konumohe, Paera Kaata, 25kg / Paera, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko te Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) he momo tote sulfate o atazanavir he tino whiriwhiringa HIV-1 te aukati protease, ko te aukati protease tuatahi i whakaaetia mo te whakahaere kotahi-ra.Ko te Atazanavir Sulfate he taputapu me te aukati o te CYP3A4, me te aukati me te whakangao i te P-glycoprotein (P-gp).Ko te Atazanavir Sulfate ano he aukati SARS-CoV 3CLpro me te IC50 o te 3.49 μM.Ko te Atazanavir Sulfate he azapeptide me te HIV-protease inhibitor e whakamahia ana i roto i te maimoatanga o nga mate HIV me te AIDS i roto i te whakakotahi me etahi atu Anti-HIV Agents, kua whakawhanakehia, kua whakarewahia e Bristol-Myers Squibb (BMS), i raro i te raihana o te ao mai i Novartis, mo te maimoatanga o te mate HIV.I whakarewahia a Atazanavir ki te US hei Reyataz™ i te Hūrae 2003. Antiviral.Ko te Atazanavir kua kitea he kaha ake te kaha atu i nga aukati HIV-1 e rima kua whakaaetia inaianei.Ko te Atazanavir he aukati i te tukatuka motuhake o te Gag me te Gag-Pol polyproteins i roto i nga ruma kua pangia e te HIV-1 ma te here ki te waahi kaha o te HIV-1 protease, na reira ka aukati i te hanganga o nga wahine pakeke.Kaore a Atazanavir i te kaha ki te mate HIV-2.