Betamethasone CAS 378-44-9 Purity 97.0%~103.0% API Factory High Purity

Whakaahuatanga Poto:

Ingoa matū: Betamethasone

CAS: 378-44-9

Te ahua: Paura ma, tata ranei ma te kirikiriata

Maamaa: 97.0%~103.0% o C22H29FO5, i runga i te maroke

API Kounga Teitei, Hanganga Tauhokohoko

Whakapā: Takuta Alvin Huang

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E-Mail: alvin@ruifuchem.com

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378-44-9 - Whakaahuatanga:

Ko te Betamethasone Taonga Tauhokohoko me te Maama me te Kounga Pumau
Ingoa matū: Betamethasone
CAS: 378-44-9

378-44-9 -Ngā Āhuatanga matū:

Ingoa matū	Betamethasone
Nga kupu taurite	Betamethasone Base;9alpha-Fluoro-16beta-Methylprednisolone;9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione;(11beta,16alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
Tau CAS	378-44-9
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C22H29FO5
Taumaha rāpoi	392.47
Iwi Whakarewa	235.0~237.0 ℃
Tikanga Tukunga	I raro i te Paemahana Ambient
COA & MSDS	Kei te waatea
Waitohu	Ruifu Chemical

378-44-9 -Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Paura ma, tata ma ranei te kirikiriata
Tautuhi A	Te horonga Infrared
Tautuhinga B	Whakamātautau Tohu Chromatographic Papa Angiangi
Hurihanga Optical Tauwhāiti	+118.0° ki te +126.0° (Kua Tatauhia i runga i te Turanga maroke)
Te poke takitahi	≤1.00%
Nga poke katoa	≤2.00%
Wairewa Wairewa Mewaro	≤3000ppm
Wairewa Wairewa Chloroform	≤60ppm
Ngaronga i te whakamaroke	≤0.50% (Me whakamaroke ki te 105 ℃, 3 haora)
Te toenga i runga i te mura	≤0.20%
Te Maama / Tikanga Tatauria	97.0%~103.0% o C22H29FO5 Kua Tātaihia i runga i te Hanga maroke
Paerewa Whakamatau	Hainamana Pharmacopoeia (CP);EP10.0 me USP 42
Te Paakara me te Rokiroki	Whakaorangia i roto i nga ipu kiki.Rokiroki i waenga i te 2 ℃ me te 30 ℃ .
Taupānga	Mahinga Rongoa Hohe (API)

Mōkī me te Rokiroki:

Mōkī:Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke (2~30 ℃) me te hau pai kia matara atu i nga matū hotokore.Mawehe atu i te marama kaha me te wera, te makuku.
Tukunga:Tukuna ki te ao ma te rangi, ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.

Painga:

FAQ:

378-44-9 - Morearea me te Haumaru:

Waehere Morearea R40 - Nga taunakitanga iti mo te paanga mate pukupuku
R48/20/21 -
R61 - Ka kino pea te tamaiti kare i whanau
Whakaahuatanga Haumaru S22 - Kaua e pupuhi puehu.
S36 - Mau kakahu whakamarumaru tika.
S45 - Ki te aituā, ki te kore koe e pai, rapua he tohutohu hauora (whakaatuhia te tapanga ina taea.)
S53 - A ape i te rongo - whiwhi tohutohu motuhake i mua i te whakamahi.
WGK Tiamana 2
RTECS TU4000000
Waehere HS 2937229000
Paitini LD50 waha i te kiore: > 4500mg/kg

378-44-9 -Taupānga:

Ko te Betamethasone (CAS: 378-44-9), no te adrenal corticosteroids, he isomer o te dexamethasone, a ko te mahi o te betamethasone he rite ki te prednisolone me te dexamethasone, he anti-inflammatory, anti-rheumatic, anti-pawera me te pehi. o te aukati me etahi atu rongoa rongoa, he kaha ake tona paanga anti-inflammatory i te dexamethasone, triamcinolone, hydrocortisone me etahi atu, ka taea e ia te whakaiti me te aukati i te urupare o te kiko ki te mumura me te whakakore i te wera, te whero me te pupuhi i puta mai i te mumura kore-mate o te rohe, na reira ka whakaiti te mahi o te mumura, te hua anti-inflammatory o tenei hua 0.3mg he rite ki te dexamethasone 0.75mg, prednisone 5mg ranei 25mg cortisone .Ko te painga o te pupuri konutai Betamethasone he rau nga wa nui atu i te hydrocortisone, i roto i te hypofunction adrenal tuatahi, ka taea te whakamahi tahi me te glucocorticoid mo te rongoa whakakapi, ka whakamahia mo te aukati, te aukati ranei i te urupare aukati-a-waea, te whakaroa i nga tauhohenga mate mate me te whakaiti i te aukati tuatahi. te roha whakautu, ka whakamahia mo te renin iti me te mate aldosterone iti me te neuropathy autonomic i whakaawehia te hypotension orthostatic.I tenei wa kei te whakamahia ano te betamethasone mo te maimoatanga o te mate rūmātiki kaha, te rumati rūmātiki, te lupus, te mate huango nui, te mate mate kino, te kanisi mate, te dermatitis atopic, te eczema, te neurodermatitis, te dermatitis seborrheic, me te pruritus me te maimoatanga matawhānui o etahi mate.Ko te hua he aukati i roto i te hitori o te hinengaro nui, te whewhe duodenal kaha, te anastomosis gastrointestinal hou, te osteoporosis taumaha, te mate huka nui, te whakaheke toto nui, te huaketo, te huakita, nga mate harore kaore e taea te whakahaere ma te whakamahi i nga raau antimicrobial, thrombophlebitis, mate kiri, penei penei i te impetigo, te tinea, te patito me etahi atu.

378-44-9 - USP35 Paerewa:

Betamethasone
C22 H29FO5 392.46
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11,16)-.
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione [378-44-9].
Kei roto te Betamethasone kaua e iti iho i te 97.0 paiheneti me te kore e neke ake i te 103.0 paiheneti o C22H29FO5, ka tatauhia i runga i te tikanga whakamaroke.
Packaging me te rokiroki-Tiaki i roto i nga ipu kiki.Rokiroki i waenga i te 2 ℃ me te 30 ℃.
Paerewa Tohutoro USP <11>-
USP Betamethasone RS
Tautuhinga-
A: Whakangao Infrared <197M>.
B: Whakamātautau Tautuhi Chromatographic Papa Angiangi <201>-
Te otinga whakamatautau-Whakaritea he otinga o te Betamethasone i roto i te waipiro maroke he 0.5 mg ia mL.
Te whakawhanake i te punaha whakarewa: he ranunga o te chloroform me te diethylamine (2:1).
Tikanga-Haere tonu ki te whakahau i roto i te upoko, engari ki te kimi i nga waahi ma te rehu ngawari ki te waikawa sulfuric waimeha (1 i roto i te 2) me te whakamahana i runga i te pereti wera, i raro ranei i te rama kia puta ra ano nga wahi.
Te hurihanga motuhake <781S>: i waenga i te +118 me te +126, ka tatauhia i runga i te whakamaroke.
Te otinga whakamatautau: 5 mg ia mL, i roto i te mewaro.
Ngaronga i runga i te whakamaroke 731-Ka whakamaroke ki te 105 mo te 3 haora: kaua e neke ake i te 1.0% o tona taumaha.
Te toenga i runga i te mura 281: kaua e neke ake i te 0.2%, ka whakamahia he ipu konukawata.
Ko nga poke noa 466-
Te otinga whakamatautau: methanol.
Te otinga paerewa: mewaro.
Rōrahi tono: 10 µL.
Eluant: he ranunga o te toluene, te acetone, te methyl ethyl ketone, me te waikawa formic (55:20:20:5), i roto i te ruuma kore.
Whakaaturanga: 5.
whakamātautau-
Wāhanga pūkoro-Whakaritea he ranunga kua tātarihia, kua whakahekehia te wai me te acetonitrile (63:37).Whakaritea nga whakarereketanga mehemea e tika ana (tirohia te Tikanga Pūnaha i raro i te Chromatography 621).
Wairewa paerewa o roto-Whakaritea he otinga o te propylparaben i roto i te waipiro e mohiotia ana mo te 0.25 mg ia mL.
Whakariterite Paerewa-Warekahia te rahinga tika o te USP Betamethasone RS i roto i te waipiro kia whiwhi ai i tetahi otinga e mohiotia ana mo te 0.2 mg ia mL.Whakawhitihia te 10.0 mL o tenei wairewa ki tetahi ipu pai, ka tapirihia te 10.0 mL o te wairewa paerewa-a-roto, kia whiwhi i te whakaritenga Paerewa e mohiotia ana ko te 0.1 mg o te betamethasone me te 0.125 mg o te propylparaben mo ia mL.
Whakaritea Whakamatau-Whakamahi mo te 80 mg o te Betamethasone, ka paunatia tika, te whakarite kia rite ki te whakarite mo te whakaritenga Paerewa.
Pūnaha Chromatographic (tirohia Chromatography 621)-Ko te chromatograph wē he mea whakakakahu ki te 240-nm kaitahuri me te 4.6-mm × 25-cm tīwae kei roto te whakakī L1.Ko te tere rere he 1.0 mL ia meneti.Chromatograph te Whakariterite Paerewa, ka tuhi i nga whakautu teitei i runga i te tohutohu mo te Tikanga: ko nga wa pupuri e pa ana ki te 1.0 mo te betamethasone me te 1.4 mo te propylparaben;ko te whakatau, R, i waenga i te betamethasone me te propylparaben kaua e iti iho i te 3.0;me te inenga paerewa mo nga werohanga tukurua kaua e neke ake i te 2.0%.
Tikanga-Tukuhia wehe nga pukapuka rite (e tata ana ki te 10 µL) o te whakaritenga Paerewa me te whakaritenga Whakatau ki te chromatograph, tuhia nga chromatograms, me te ine i nga whakautu mo nga tihi nui.Tātaihia te rahinga, i te mg, o C22H29FO5 i te wahanga o te Betamethasone i tangohia e te tauira:
800C(RU / RS)
ko C te kukū, i te mg ia mL, o te USP Betamethasone RS i roto i te whakaritenga Paerewa;me te RU me te RS ko nga reanga teitei teitei o te peak betamethasone me te tihi paerewa o roto i whiwhi mai i te whakaritenga Assay me te whakaritenga Paerewa, ia.