Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer
Ko te Kaihanga Kaihanga me te Maama me te Kounga Pumau
Ingoa: Bicalutamide
CAS: 90357-06-5
Bicalutamide i roto i te maimoatanga o te mate pukupuku Prostate Advanced
API Kounga Teitei, Hanganga Tauhokohoko
Ingoa | Bicalutamide |
Nga kupu taurite | N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide |
Tau CAS | 90357-06-5 |
Tau CAT | RF-API76 |
Tūnga Taonga | Kei roto i nga taonga, ka eke ki te rau kirokaramu |
Tātai rāpoi | C18H14F4N2O4S |
Taumaha rāpoi | 430.37 |
Paemahana Rokiroki | 2-8 ℃ |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Paura Tioata-White |
Tautuhi A | IR: He rite te hihinga o te tauira ki te paerewa tohutoro |
Tautuhinga B | HPLC: Ko te wa pupuri o te tihi nui o te otinga tauira e rite ana ki tera o te otinga paerewa |
Tautuhinga C | Te Tautuhinga Pukuoro Organic |
Wairewa | Ka Rere noa i roto i te Acetone me te Tetrahydrofuran, He iti te Rere ki te Ethyl Acetate |
Iwi Whakarewa | 191.0~195.0℃ |
Ihirangi Wai (na KF) | ≤0.20% |
Ihirangi Fluoride | 15.9%~18.5% |
Ngaronga i te whakamaroke | ≤0.50% |
Te toenga i runga i te mura | ≤0.10% |
Nga Korewa Taamaha | ≤10ppm |
Wairewa toenga | |
Tetrahydrofuran | ≤0.072% |
Toluene | ≤0.089% |
N-Hexane | ≤0.029% |
Acetone | ≤0.50% |
Ethyl Acetate | ≤0.50% |
Nga Taonga Paanga | |
N,N'-Dimethyl Acetamide | ≤0.109% |
Bicalutamide Aminobenzonitrile | ≤0.10% |
Ko te Huihuinga Bicalutamide A Isomer A | ≤0.10% |
Bicalutamide Pānga Puhui A Isomer B | ≤0.10% |
Desfluoro Bicalutamide | ≤0.20% |
2-Fluoro Bicalutamide | ≤0.20% |
Deoxy Bicalutamide | ≤0.20% |
Bicalutamide Sulfide | ≤0.10% |
Tetahi poke kore i tohua | ≤0.10% |
Nga poke katoa | ≤0.50% |
Rahi Matūriki | 90%<10um;50%<5um |
Te whakamatautau | 98.0%~102.0% (i runga i te whakamaroke) |
Nga Whakamatau Microbiological | |
Tatau Aerobic Ka taea | ≤500CFU/g |
Rewena me nga Maaka | ≤50CFU/g |
Te Ora Papa | 24 Marama |
Paerewa Whakamatau | Paerewa hinonga;USP Paerewa |
Whakamahinga | API, i roto i te maimoatanga o te mate pukupuku Prostate Advanced |
Mōkī: Pounamu, Peeke konumohe konumohe, Pahu Kaata, 25kg / Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Whakaorangia mai i te marama, te makuku me te mate kino.
Ko te Bicalutamide (CAS: 90357-06-5) he antagonist androgen kore-steroidal, e whakataetae ana i te kaitautoko androgen me te androgen, ka aukati i te tango i te pūtau o te androgen, me te aukati i te herenga o nga androgens ki te okana whaainga.Ka herea ki te kaikawe androgen e hanga ana i te matatini kaikawe, ka uru ki roto ki te karihi ka honoa ki te nucleoprotein, na reira ka aukati i te tipu o nga pūtau puku.Ka waiho hei rongoa rarangi tuatahi mo te maimoatanga whakamaarama mo te mate pukupuku repeure matatau.I whakarewahia a Bicalutamide i te United Kingdom, ko tana maakete tuatahi o te ao, mo te maimoatanga o te mate pukupuku prostate matatau i te taha o te LHRH tairitenga me te whakamaoritanga pokanga.Ko te antiandrogen kore-steroidal, ko te kowhiri i te taha o te taha, ko te bicalutamide te aukati i te mahi o te dihydrotestosterone me te testosterone i nga waahi whaainga ma te whakataetae whakataetae ki te kaiwhakawhiwhi androgen cytosolic.E ai ki te korero, he pai te whakamanawanui me te kore o nga paanga o te mate ngakau me te metabolic na te korenga o nga mahi steroid.Kua whakaatuhia te kaha o te bicalutamide hei monotherapy.I purongohia ano nga reeti whakautu pai mo te rongoa i nga mate pukupuku pukupuku, te u, te pancreas me nga mate pukupuku pūkahukahu kore-iti.