Brexpiprazole CAS 913611-97-9 Purity >99.0% (HPLC) API Factory

Whakaahuatanga Poto:

Ingoa matū: Brexpiprazole

CAS: 913611-97-9

Maamaa: >99.0% (HPLC)

Te ahua: Paura Tioataata Maama ranei

API Kounga Teitei, Hanganga Tauhokohoko

E-Mail: alvin@ruifuchem.com

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Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-kotahi CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3

Ngā Āhuatanga matū:

Ingoa matū	Brexpiprazole
Nga kupu taurite	OPC-34712;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one
Tau CAS	913611-97-9
Tau CAT	RF-PI1982
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C25H27N3O2S
Taumaha rāpoi	433.57
Kiato	1.245±0.060 g/cm3
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Te Paura Maama, Maama-Ma ranei
Tautuhinga	Na IR
RT	I raro i te aroha me whai
pūhaumāota	Ka hoatu he tauhohenga o te pūhaumāota
Wai	3.0%~4.5%
Iwi Whakarewa	198.0~202.0 ℃
Te toenga i runga i te mura	<0.20%
Nga Korewa Taamaha	≤10ppm
Nga Taonga Paanga
Te poke takitahi	<0.50%
Nga poke katoa	<1.00%
EE	>99.0%
Te Maama / Tikanga Tatauria	>99.0% (HPLC, kia maroke)
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	API

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

Painga:

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Taupānga:

Ko Brexpiprazole (CAS: 913611-97-9) he kaitono tarukino whai hua ki te maimoatanga me te aukati i nga mate hinengaro tae atu ki nga mate CNS.Ko te Brexpiprazole he rongoa antipsychotic hou e mahi ana hei serotonin ® dopamine mahi modulator me te whakaatu i te kaha hei maimoatanga taapiri mo nga turoro me te mate pouri nui (MDD).Ko te Brexpiprazole e whakaatu ana i tetahi tohu rongoa ahurei, e mahi ana hei agonist wahanga o te serotonin 5-HT1A me te dopamine D2 receptors me te rite ki te tino antagonist o 5-HT2A me te noradrenaline α1B / 2C receptors, he rite te hononga here subnanomolar.I whakawhanakehia a Brexpiprazole e Otsuka me Lundbeck, i whakaaetia i te 2015 e te FDA mo te maimoatanga o te schizophrenia me te maimoatanga taapiri mo te pouri.Ko te Brexpiprazole e kiia ana he kai-riiwhi mo te rongoa a Otsuka antipsychotic aripiprazole (ingoa hokohoko Abilify) i pau tana patent i Akuhata 2014.