Candesartan CAS 139481-59-7 Purity >99.0% (HPLC) wheketere
Ruifu Chemical Supply Candesartan Cilexetil Intermediate With High Pure
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0
Ingoa matū | Candesartan |
Nga kupu taurite | CV-11974;2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-Carboxylic Acid;3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-Benzimidazole-4-Carboxylic Acid;Candesartan M1;Candesartan Cilexetil EP Te poke G |
Tau CAS | 139481-59-7 |
Tau CAT | RF-PI1889 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C24H20N6O3 |
Taumaha rāpoi | 440.45 |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura ma |
Tautuhinga-HPLC | Te Wā Pupuri He rite ki te Paerewa |
Tautuhi-IR | He rite ki te Paerewa |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Te Whakarewa | 183.0~185.0℃ |
Ngaronga i te whakamaroke | <0.50% |
makuku (KF) | <0.50% |
Te toenga i runga i te mura | <0.50% |
Nga Korewa Taamaha | <20ppm |
Te poke takitahi | <1.00% (HPLC) |
Nga poke katoa | <1.00% (HPLC) |
Taurangi Refactive | n20/D 1.745~1.747 |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | API;Mo te maimoatanga o te mate toto |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
Ko Candesartan (CAS: 139481-59-7) he angiotensin II receptor antagonist me IC50 o 0.26 nM.Whainga: Ko te Angiotensin II Receptor candesartan e tohuhia ana mo te maimoatanga o te whakaheke toto.I whakaaetia tuatahi a Candesartan Cilexetil i GB i te Apr 29, 1997, katahi ka whakaaetia e te US Food and Drug Administration (FDA) i te Hune 4, 1998, ka whakaaetia e te Pharmaceuticals and Medical Devices Agency of Japan (PMDA) i te Maehe 12, 1999. I whakawhanakehia e AstraZeneca, ka hokona hei Atacand e AstraZeneca i GB me te US, ka hokona hei Blopress na Takeda i JP.Ko te Candesartan Cilexetil he angiotensin II receptor blocker (ARB), ka aukati i te vasoconstrictor me nga aldosterone-secreting effects o angiotensin II ma te aukati i te herenga o te angiotensin II ki te kaiwhakawhiwhi AT1 i roto i te maha o nga kopa, penei i te uaua maeneene me te repe adrenal.Ko te Atacand e tohuhia ana mo te maimoatanga o te whakaheke toto i roto i nga pakeke me nga tamariki 1 ki te <17 tau te pakeke, te ngoikore o te ngakau (NYHA class II-IV) ka whakamahia hei whakaiti i te mate o te mate cardiovascular me te mate o te ngakau o te hohipera.