Candesartan Cilexetil CAS 145040-37-5 Purity >99.0% (HPLC) API Factory

Whakaahuatanga Poto:

Ingoa matū: Candesartan Cilexetil

CAS: 145040-37-5

Maamaa: >99.0% (HPLC)

Te ahua: Ma ki te Paura Tioataata-Ma

He Angiotensin II Receptor Antagonist whiriwhiri

API Kounga Teitei, Hanganga Tauhokohoko

E-Mail: alvin@ruifuchem.com

Tukuna he imeera ki a matou

Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ruifu Chemical Supply Candesartan Cilexetil Intermediate With High Pure
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0

Ngā Āhuatanga matū:

Ingoa matū	Candesartan Cilexetil
Nga kupu taurite	TCV-116;1-(((((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H -benzo[d]imidazole-7-Carboxylate
Tau CAS	145040-37-5
Tau CAT	RF-PI1891
Tūnga Taonga	I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi	C33H34N6O6
Taumaha rāpoi	610.66
Waitohu	Ruifu Chemical

Whakatakotoranga:

Tūemi	Whakatakotoranga
Te ahua	Ma ki te Paura Tioata-White
Tautuhinga HPLC	Ko te wa pupuri o te tihi nui i roto i te chromatogram o te tauira e rite ana ki tera i te chromatogram i whiwhi me te paerewa
Tautuhinga IR	IR infrared absorption spectrum he rite ki tera o te paerewa tohutoro Candesartan Cilexetil
Te Maama me te Rongoa Tae	Ko te otinga i roto i te chloroform i te 5% he maamaa me te kore tae
Te Maama / Tikanga Tatauria	>99.0% (HPLC)
Iwi Whakarewa	155.0~160.0℃
Ngaronga i te whakamaroke	<0.30%
Te toenga i runga i te mura	<0.10%
Nga Korewa Taamaha	<10ppm
Arsenic (As)	<1ppm
Te Tohatoha Rahi Matūriki	90% <30 μm
Nga poke pararopi	na HPLC
Ethyl Candesartan	<0.15%
Desethyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
Tetahi poke kore mohiotia	<0.15%
Nga poke katoa	<0.60%
Te whakamatautau ma te Potentiometry	99.0~101.0% o C33H34N6O6, kua tatauhia i runga i te matū waikore
Te poke parakore
Methano	<0.30%
Ewaro	<0.50%
Diethyl Etera	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Whakamaoritanga Microbiological
Tatau Moroiti Aerobic Tapeke	<1000cfu/g
Maaka me te rewena	<100cfu/g
E.Coli	Kei te ngaro
Haramona	Kei te ngaro
Paerewa Whakamatau	Paerewa hinonga
Whakamahinga	API;Te Kaipupuri Atete

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku

Painga:

FAQ:

Taupānga:

Ko Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) he angiotensin II receptor antagonist me te IC50 o te 0.26 nM, e whakamahia ana i roto i te maimoatanga o te whakaheke toto.Ko te Candesartan he angiotensin-receptor blocker (ARB) ka taea te whakamahi takitahi me etahi atu raau taero ki te rongoa i te whakaheke toto.Ka whakahaerehia ma te waha hei prodrug, candesartan cilexetil, ka tere te huri ki tana metabolite kaha, candesartan, i te wa e whakauru ana i roto i te gastrointestinal tract.Ka whakahekehia e Candesartan te pehanga toto ma te whakaeke i te punaha renin-angiotensin-aldosterone (RAAS);ka whakataetae ki te angiotensin II mo te here ki te momo-1 angiotensin II receptor (AT1) subtype me te aukati i te pehanga toto e piki ake nga paanga o te angiotensin II.Kaore i te rite ki te aukati angiotensin-converting enzyme (ACE), karekau he painga kino o te maremare o te ARB.Ka taea te whakamahi Candesartan ki te rongoa i te takawhita, te takawhita systolic taratahi, te hypertrophy ventricular maui me te nephropathy mate huka.Ka taea ano te whakamahi hei kaihoko rereke mo te maimoatanga o te ngoikore o te ngakau, te ngoikoretanga o te systolic, te infarction myocardial me te mate pukupuku coronary.