Daclatasvir Dihydrochloride Intermediate CAS 1007882-23-6 Purity >98.0% (HPLC)
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o Daclatasvir Dihydrochloride Intermediate (CAS: 1007882-23-6) me te kounga teitei.Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te iti me te rahinga e waatea ana.Hokona Daclatasvir Dihydrochloride Intermediates,Please contact: alvin@ruifuchem.com
| Ingoa matū | Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) |
| Nga kupu taurite | Daclatasvir Intermediate Ⅱ;Dacaltasvir Intermediate 02;Daclatasvir T-Butyl Ester;Bis(2-Methyl-2-Propanyl) (2S,2'S)-2,2'-[4,4'-Biphenyldiylbis(1H-Imidazole-4,2-diyl)]di(1-Pyrrolidinecarboxylate);Di-tert-butyl 2,2′-([1,1′-Biphenyl]-4,4′-diylbis(1H-Imidazole-5,2-diyl))(2S,2'S)-bis(Pyridineidine-1- Carboxylate);(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-Imidazole-5,2-diyl)bis-1-Pyrrolidinecarboxylic Acid 1,1'-Bis (1,1-Dimethylethyl) Ester;Daclatasvir poke 4 |
| Tūnga Taonga | I roto i te Stock, Production Arumoni |
| Tau CAS | 1007882-23-6 |
| Tātai rāpoi | C40H51ClN8O6 |
| Taumaha rāpoi | 775.35 g/mol |
| Kohuatanga | 890.2±65.0 ℃ i te 760 mmHg |
| Kiato | 1.220±0.06 g/cm3 |
| COA & MSDS | Kei te waatea |
| Taketake | Shanghai, Haina |
| Kāwai | Takawaenga o Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Waitohu | Ruifu Chemical |
| Nga taonga | Whakatakotoranga | Hua |
| Te ahua | Kowhai Maama ki te Paura Kowhai | Paura Kōwhai Maama |
| Ngaronga i te whakamaroke | <1.00% | 0.65% |
| Mōrahi Kore kotahi | <1.00% | 0.45% |
| Nga poke katoa | <2.00% | 1.24% |
| Te Maama / Tikanga Tatauria | >98.0% (HPLC) | 98.76% |
| Spectrum Infrared | E rite ana ki te Hanganga | Ka tutuki |
| 1H NMR Spectrum | E rite ana ki te Hanganga | Ka tutuki |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua | |
| Taupānga | Takawaenga o Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Mōkī:Pounamu Fluorinated, Peeke pepa konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati tonu te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke me te hau pai kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.
Tukunga:Tukuna ki te ao ma te rangi, ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) (CAS: 1007882-23-6) he takawaenga o Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Kua whiwhi a Daclatasvir (Daklinza) i te mana "arotake matua", i honoa me Sorafenib mo te maimoatanga o nga turoro pakeke III ira me te mate pukupuku C. Ko Daklinza te rongoa tuatahi kua whakamatauhia he whai hua ki te maimoatanga o te mate pukupuku III mate pukupuku C. te mate me te kore te whakahaere tahi me te interferon me te ribavirin ranei.Ko te Interferon me te Ribavirin e rua nga raau taero kua whakaaetia e te FDA mo te maimoatanga o te mate huaketo hepatitis C.Ko te Hepatitis C he mate kino ka puta te mumura o te ate, ka heke te mahi ate, te mate ate ranei.Ko te nuinga o nga turoro kua pangia e te mate hepatitis C karekau he tohu kia kitea ra ano te kino o te ate, ka roa pea nga tau.I te ao katoa, ko te momo momo ira momo III kakā C te tuarua o te momo momo momo mate kakā C i muri i te momo momo mate 1 kakā C, ka kiia ko tetahi o nga mate momo momo tino whakakeke.Ko Daklinza he pan-genotype NS5A te aukati matatini, me te kaha o te aukati i te tukuruatanga o te RNA me te huihuinga viral, rua nga hua antiviral.Mo nga rangahau in vitro, kua whakaatuhia a Daklinza ki te whai hua anti-viral ki te ira momo 1~6 mate hepatitis C.Kei te haere tahi a Daklinza me te whakatupato ko te whakakotahitanga o te amiodarone, Daklinza me Sofosbuvir ka nui te heke o te ngakau.Ko Daklinza he papa-waha me te horopeta e taunakitia ana mo te 60 mg mo te 1 wa/d, i te taha o Sofosbuvir mo te katoa o nga wiki 12.
Kamupene rangahau me te whanaketanga: Bristol-Myers Squibb.
Tuhituhi Patent: WO 2008021927A2 (Akuhata 9, 2007).
Te wa o te hokohoko: Hōngongoi 24, 2015 kua tuhia ki te United States, ingoa hokohoko Daklinza.
Nga tohu: Ka whakamahia ki te taha o te Sofosbuvir mo te maimoatanga o te mate pukupuku 3 mate pukupuku C (HCV).
Mahinga mahi: HCV pūmua kore hanganga 5A (NS5A) aukati.Nga tauhohenga kino: te mahunga me te ngenge.
Te hanga me nga whakaritenga: Papa, 30 me te 60mg.
