4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid CAS 123654-26-2 Prucalopride Succinate Intermediate Purity ≥98.0% (HPLC)
Ko Shanghai Ruifu Chemical te kaihanga matua o 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid (CAS: 123654-26-2) me te kounga teitei.Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona nga takawaenga Prucalopride Succinate,Please contact: alvin@ruifuchem.com
| Ingoa matū | 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid |
| Nga kupu taurite | 4-Amino-5-Chlorocoumaran-7-Carboxylic Acid;4-Amino-5-Chloro-2,3-Dihydrobenzo[b]furan-7-Carboxylic Acid;4-Amino-5-Chloro-2,3-Dihydro-1-Benzofuran-7-Carboxylic Acid;4-Amino-5-Chloro-2,3-Dihydro-7-Benzofurancarboxylic Acid;Prucalopride poke A;Prucalopride Succinate poke-2 |
| Tūnga Taonga | I roto i te Stock, Production Arumoni |
| Tau CAS | 123654-26-2 |
| Tātai rāpoi | C9H8ClNO3 |
| Taumaha rāpoi | 213.62 g/mol |
| Iwi Whakarewa | 242℃(tiki) |
| Kohuatanga | 406.5±45.0℃ |
| Kiato | 1.566 |
| COA & MSDS | Kei te waatea |
| Taketake | Shanghai, Haina |
| Kāwai | Takawaenga o Prucalopride Succinate (CAS: 179474-85-2) |
| Waitohu | Ruifu Chemical |
| Nga taonga | Nga Paerewa Tirotiro | Hua |
| Te ahua | Maama-Ma ki te Maama-Whero Solid | Mārō-Whero Mārō |
| Wai na Karl Fischer | ≤1.00% | 0.35% |
| Te toenga i runga i te mura | <0.20% | 0.08% |
| Konga Taamaha (Pb) | ≤20ppm | <10ppm |
| Te poke kotahi | ≤1.00% | Ka tutuki |
| Nga poke katoa | ≤2.00% | Ka tutuki |
| Te Maama / Tikanga Tatauria | ≥98.0% (HPLC) | 99.6% |
| Spectrum Infrared | He rite ki te Hanganga | Ka tutuki |
| 1 H NMR Spectrum | He rite ki te Hanganga | Ka tutuki |
| Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua | |
Mōkī:Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke (2~8 ℃) me te hau pai kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.
Tukunga:Tukuna ki te ao ma te rangi, ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Ko tenei hua ko te 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid, ko te ihirangi o C12H12ClNO4 kaua e iti iho i te 98.0%, ka tatauhia i runga i te kaupapa anhydrous.
[Properties] Ko tenei hua he ma-ma ki te maama-whero totoka.
[Tirohia]
Tangohia he nui e tika ana o tenei hua (mo te 0.5g) o te wai, tāpirihia te whakarewa (methanol: N,N-dimethylformamide = 50:50), ka memeha i runga i te tikanga whakatau wai (Apitihanga Ⅷ M, tikanga tuatahi A).Whakamahia nga pata whakamatautau a Fisher ki te whakatau kia huri ra ano te otinga mai i te kowhai marama ki te whero-parauri e tohu ana i te pito mutunga, ka whakahaere i tetahi atu whakamatautau paratea.Tātaihia kia rite ki te tauira e whai ake nei: kaua e neke ake i te 1.00%.
Ihirangi makuku (%) = (AB) F/W×100%
Inaa, ko A te rōrahi o te wai a Fisher i pau i te hua whakamātautau (ml);
Ko B te rōrahi o te wai whakamātautau a Fisher i pau i te wāhi pātea, ml;
F ko te taumaha o te otinga whakamatautau a Fisher e rite ana ki te wai mo ia 1ml, mg;
Ko te W te taumaha o te hua whakamatautau, mg
Matū whai pānga
E ai ki te tikanga i raro i te "Tuemi inenga Ihirangi", mena he tihi poke kei roto i te chromatogram o te otinga whakamatautau, ko te waahi teitei o te poke kotahi kaua e nui ake i te 10 nga wa (1.0%) o te waahi tihi matua o te mana whakahaere. otinga, me te tapeke o te waahi tihi o nga poke katoa kia kaua e nui ake i te 20 wa (2.0%) o te waahi tihi matua o te otinga whakahaere.
[Whakataunga Ihirangi] E ai ki te chromatography wai mahi teitei (Appendix VI D).
I whakamahia te kirikiri herea Octadecylsilane hei whakakii mo nga ahuatanga chromatographic me nga whakamatautau pai o te punaha.Ko te otinga parepare Phosphate (1.36g te pāhare pāporo dihydrogen phosphate, te ultrasonic rewa i roto i te wai 1L, te waikawa phosphoric i whakaritea ki te PH 3.0) i whakamahia hei wahanga pūkoro A. Ko te Acetonitrile te wahanga pūkoro B, ka mahia te rerenga rōnaki kia rite ki te ripanga e whai ake nei:
Wā (min) Wāhanga pūkoro A Wāhanga pūkoro B
0 80 20
15 80 20
30 50 50
45 50 50
Ko te roangaru kitea he 254 nm.Ko te rerenga rere ko 1.0 ml / min.Ko te maha o nga pereti ariā e kore e iti iho i te 2000 e ai ki te tihi o te 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid
Ko te tihi o te waikawa furanoformic kaua e iti iho i te 2000.
Tikanga whakatau:
Tangohia te 10mg o te hua whakamatautau, pauna tika, hoatu ki roto i te pounamu A 10ml, whakakorehia te ultrasonic me te wahanga pūkoro A-waahanga pūkoro B (70:30) hei whakarewa, waimeha ki te tauine, ruru pai, ka takai he otinga ki te kukū o 1mg/ml.20 l o te tino tika i werohia ki roto i te chromatograph wai, ka tuhia te chromatogram.Ko te parakore o te tihi matua kaore i iti iho i te 98.0% i runga i te tikanga whakatikatika rohe tihi
Tīwae: Dionex Acclaim C18, 4.6*250mm, 5um
Te pāmahana tīwae: 40℃
Rere rere: 1.0ml/min
Te roangaru rapu: 254nm
Rahi tauira: 10μL
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid (CAS: 123654-26-2), ka taea te whakamahi hei takawaenga mo te whakahiato o Prucalopride Succinate (CAS: 179474-85-2), he agonist kaiwhakawhiwhi 5-HT4 whiriwhiri i whakamahia whai hua mo te koroka roa.Ko te Prucalopride Succinate, he dihydrobenzofurancarboxamide tuatahi-i roto i te karaehe, he rerotonin whiriwhiri (5-HT4).Ko te raau taero, i hokona i raro i te ingoa tohu Resolor®, he mahi enterokinetic a i whakawhanakehia e te umanga rongoa a Belgian Movetis.Ko te Prucalopride te whakarereke i nga tauira motika koroni na roto i te whakaihiihi kaikawe rerotonin 5-HT4, e whakaohooho ana i te kaha o te puku mo te whakaheke.
