2-Cyanophenylboronic Acid 1,3-Propanediol Ester CAS 172732-52-4 Perampanel Intermediate Purity >99.0% (HPLC)

Whakaahuatanga Poto:

2-Cyanophenylboronic Acid 1,3-Propanediol Ester

CAS: 172732-52-4

Maamaa: >99.0% (HPLC)

Te ahua: Ma ki te Maama Kowhai Paura ki te Kiriata

Takawaenga o Perampanel (CAS: 380917-97-5)

Whakapā: Takuta Alvin Huang

Pūkoro/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Taipitopito Hua

Hua e Pa ana

Tohu Hua

Whakaahuatanga:

Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o te 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) me te kounga teitei, te takawaenga o Perampanel (CAS: 380917-97-5).Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona nga takawaenga Perampanel, Please contact: alvin@ruifuchem.com

Intermediates of Perampanel:

Nga Ahuatanga matū:

Ingoa matū 2-Cyanophenylboronic Acid 1,3-Propanediol Ester
Nga kupu taurite 2-Cyanobenzeneboronic Acid 1,3-Propanediol Ester;2-(1,3,2-Dioxaborinan-2-yl)benzonitrile
Tau CAS 172732-52-4
Tūnga Taonga I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi C10H10BNO2
Taumaha rāpoi 187.01
Te Whakarewa 46.0~51.0℃ (marama)
Kiato 1.13±0.10 g/cm3
Wairewa Wairewa ki Methanol
Te pumau Hygroscopic
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua Ma ki te Maama Kowhai Paura ki te Kiriata
Te Maama / Tikanga Tatauria >99.0% (HPLC)
Ngaronga i te whakamaroke <0.50%
Te toenga i runga i te mura <0.20%
Te poke kotahi <0.50%
Nga poke katoa <1.00%
Konga Taamaha (hei Pb) <20ppm
Paerewa Whakamatau Paerewa hinonga
Whakamahinga Takawaenga o Perampanel (CAS: 380917-97-5)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.

Painga:

1

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172732-52-4 - Morearea me te Haumaru:

Nga Tohu Moorearea Xi - Irirangi
Waehere Morearea
R20/21/22 - He kino ma te horomia, ka pa ki te kiri me te horomia.
R36/37/38 - He whakapataritari ki nga kanohi, te punaha manawa me te kiri.
Whakaahuatanga Haumaru
S26 - Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
S36/37/39 - Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi.
UN ID 3439
WGK Tiamana 3
TSCA No
Tohu Whakamate

172732-52-4 - Taupānga:

Ko te 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) e whakamahia ana i roto i te whakahiatotanga o Perampanel (CAS: 380917-97-5), he kaitautoko AMPA receptor antagonist.Ko Perampanel (he raihana i te tau 2012) he tuatoru-whakatupuranga AED e mohiotia ana me te ingoa tohu rangatira o Fycompa® (Eisai, Hatfield) i te UK me Banzel® (Eisai, Hatfield) i te USA.I te Oketopa 2012, i whakaaetia e te US FDA te perampanel mo te maimoatanga o te hopukanga o te wahanga i nga turoro epileptic he 12 tau te iti rawa.Ko Perampanel te tuatahi o nga kaiwhaiwhai AMPA ki te whiwhi whakaaetanga FDA hei AED.Ko nga kaiwhakawhiwhi glutamate AMPA ka kitea i runga i nga neuron postsynaptic i roto i te roro.I te mea he kaitukino whiriwhiri, kore whakataetae o te AMPA, ka aukati te parampanel i te whakatuwheratanga o te hongere katote me te whakaiti i te whakawhänui o te kaha mahi.I whakaaetia a Perampanel e te Pakeha EMA me te US FDA i te marama o Hūrae me Oketopa 2012, ka whakamahia mo te maimoatanga awhina o nga turoro me te hopu i etahi waahanga neke atu i te 12 tau me te kore ranei o nga mate o te punaha tuarua.I te Hune 22, 2015, i kii a Eisai kua whakaaetia e te US FDA te whakawhänui i te tohu o te Pirenparanide hydrate (Fycompa) hei maimoatanga awhina mo nga hopukanga tonic-clonic matawhānui tuatahi i roto i nga turoro me te mate pukupuku 12 me runga ake.

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