2-Cyanophenylboronic Acid 1,3-Propanediol Ester CAS 172732-52-4 Perampanel Intermediate Purity >99.0% (HPLC)
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o te 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) me te kounga teitei, te takawaenga o Perampanel (CAS: 380917-97-5).Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona nga takawaenga Perampanel, Please contact: alvin@ruifuchem.com
Ingoa matū | 2-Cyanophenylboronic Acid 1,3-Propanediol Ester |
Nga kupu taurite | 2-Cyanobenzeneboronic Acid 1,3-Propanediol Ester;2-(1,3,2-Dioxaborinan-2-yl)benzonitrile |
Tau CAS | 172732-52-4 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C10H10BNO2 |
Taumaha rāpoi | 187.01 |
Te Whakarewa | 46.0~51.0℃ (marama) |
Kiato | 1.13±0.10 g/cm3 |
Wairewa | Wairewa ki Methanol |
Te pumau | Hygroscopic |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Ma ki te Maama Kowhai Paura ki te Kiriata |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Ngaronga i te whakamaroke | <0.50% |
Te toenga i runga i te mura | <0.20% |
Te poke kotahi | <0.50% |
Nga poke katoa | <1.00% |
Konga Taamaha (hei Pb) | <20ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Perampanel (CAS: 380917-97-5) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.
Nga Tohu Moorearea Xi - Irirangi
Waehere Morearea
R20/21/22 - He kino ma te horomia, ka pa ki te kiri me te horomia.
R36/37/38 - He whakapataritari ki nga kanohi, te punaha manawa me te kiri.
Whakaahuatanga Haumaru
S26 - Mena ka pa ki nga kanohi, horoi tonu ki te nui o te wai me te rapu tohutohu hauora.
S36/37/39 - Mau kakahu whakamarumaru tika, karapu me te whakamarumaru kanohi/kanohi.
UN ID 3439
WGK Tiamana 3
TSCA No
Tohu Whakamate
Ko te 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) e whakamahia ana i roto i te whakahiatotanga o Perampanel (CAS: 380917-97-5), he kaitautoko AMPA receptor antagonist.Ko Perampanel (he raihana i te tau 2012) he tuatoru-whakatupuranga AED e mohiotia ana me te ingoa tohu rangatira o Fycompa® (Eisai, Hatfield) i te UK me Banzel® (Eisai, Hatfield) i te USA.I te Oketopa 2012, i whakaaetia e te US FDA te perampanel mo te maimoatanga o te hopukanga o te wahanga i nga turoro epileptic he 12 tau te iti rawa.Ko Perampanel te tuatahi o nga kaiwhaiwhai AMPA ki te whiwhi whakaaetanga FDA hei AED.Ko nga kaiwhakawhiwhi glutamate AMPA ka kitea i runga i nga neuron postsynaptic i roto i te roro.I te mea he kaitukino whiriwhiri, kore whakataetae o te AMPA, ka aukati te parampanel i te whakatuwheratanga o te hongere katote me te whakaiti i te whakawhänui o te kaha mahi.I whakaaetia a Perampanel e te Pakeha EMA me te US FDA i te marama o Hūrae me Oketopa 2012, ka whakamahia mo te maimoatanga awhina o nga turoro me te hopu i etahi waahanga neke atu i te 12 tau me te kore ranei o nga mate o te punaha tuarua.I te Hune 22, 2015, i kii a Eisai kua whakaaetia e te US FDA te whakawhänui i te tohu o te Pirenparanide hydrate (Fycompa) hei maimoatanga awhina mo nga hopukanga tonic-clonic matawhānui tuatahi i roto i nga turoro me te mate pukupuku 12 me runga ake.