6,7-Bis(2-Methoxyethoxy)-4(3H)-Quinazolinone CAS 179688-29-0 Erlotinib Hydrochloride Intermediate Purity >99.0% (HPLC)
Kaihanga rangatira me te kaiwhakarato o Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
Please contact: alvin@ruifuchem.com
Ingoa matū | 6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one |
Nga kupu taurite | 6,7-Bis(2-Methoxyethoxy)-4(3H)-Quinazolinone;6,7-Bis(2-Methoxyethoxy)-3,4-Dihydroquinazolin-4-one;6,7-Bis(2-Methoxyethoxy)-4-Hydroxyquinazoline;6,7-Bis(2-Methoxyethoxy)-4-Quinazolinol;CP-380736 |
poke | Erlotinib poke A;Erlotinib Lactam poke |
Tau CAS | 179688-29-0 |
Tau CAT | RF2685 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C14H18N2O5 |
Taumaha rāpoi | 294.31 |
Iwi Whakarewa | 190.0 ki te 194.0 ℃ |
Kiato | 1.26±0.1 g/cm3 |
Tairongo | Te rangi tairongo |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Paura Ma, Paura-Ma ranei |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) |
Iwi Whakarewa | 190.0 ki te 194.0 ℃ |
Ngaronga i te whakamaroke | <0.50% |
Te toenga i runga i te mura | <0.20% |
Ko nga poke e pa ana na HPLC | |
Te poke takitahi | <0.50% |
Nga poke katoa | <1.00% |
Nga Korewa Taamaha | <10ppm |
Spectrum Infrared | He rite ki te Hanganga |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o Erlotinib Hydrochloride (CAS: 183319-69-9) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
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6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one (CAS: 179688-29-0) he takawaenga o Erlotinib Hydrochloride (CAS: 183319-69-9).Ko te Erlotinib Hydrochlorate he iti ngota ngota tyrosine kinase aukati e mahi whakamuri ana i runga i nga kaiwhakawhiwhi tauwehe tupu epidermal, he hydrochloride o te erlotinib, he raau molecular-targeted.Kua whakaaetia e te US Food and Drug Administration (FDA) te erlotinib (Tarceva) me te gemcitabine hei rongoa tuatahi mo te mate pukupuku pancreatic matatau me te metastatic.Ko te nuinga ka whakamahia hei maimoatanga tuarua, tuatoru ranei mo te mate pukupuku o te puku o te rohe, metstatic kore-iti ranei mo te mate pukupuku puku (NSCLC) me te rongoa mo te mate pukupuku pancreatic.Ka whakamahia hei aukati tyrosine mo te maimoatanga NSCLC.Ko te pūhui rāpoi iti Erlotinib Hydrochlorate ko te tyrosine kinase receptor inhibitor e aukati ana i te tipu o nga pūtau puku ma te aukati i te phosphorylation, ka herea ki te rohe catalytic intracellular o tyrosine kinase i roto i te whakataetae me te ATP, na reira ka aukati i te whakawhiti tohu o raro me te aukati i te mahi o te ligand pūtau pukupuku e whakawhirinaki ana. HER-1/EGFR.