Gefitinib Intermediate CAS 199327-61-2 Purity >99.0% (HPLC)
Ko Shanghai Ruifu Chemical Co., Ltd. te kaihanga matua o 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-One (CAS: 199327-61-2) me te kounga teitei, waenga o Gefitinib (CAS: 184475-35-2).Ka taea e Ruifu Chemical te tuku i te ao, te utu whakataetae, te ratonga pai, te iti me te rahinga e waatea ana.Hokona nga takawaenga Gefitinib,Please contact: alvin@ruifuchem.com
Ingoa matū | 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-Kotahi |
Nga kupu taurite | 7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4(3H)-Kotahi;7-Methoxy-6-[3-(4-Morpholinyl)propoxy]-4(3H)-Quinazolinone;7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4-Kotahi |
poke | Gefitinib poke 5;Gefitinib EP Pure A |
Tūnga Taonga | I roto i te Stock, Production Arumoni |
Tau CAS | 199327-61-2 |
Tātai rāpoi | C16H21N3O4 |
Taumaha rāpoi | 319.36 g/mol |
Iwi Whakarewa | 242.0~247.0 ℃ |
Kiato | 1.32±0.10 g/cm3 |
COA & MSDS | Kei te waatea |
Taketake | Shanghai, Haina |
Waitohu | Ruifu Chemical |
Nga taonga | Nga Paerewa Tirotiro | Hua |
Te ahua | Ma ki te Paura-White | Ka tutuki |
Iwi Whakarewa | 242.0~247.0 ℃ | 243.6~244.5℃ |
Ngaronga i te whakamaroke | <0.50% | 0.15% |
Te toenga i runga i te mura | <0.20% | 0.11% |
Te poke kotahi | <0.50% | <0.30% |
Nga poke katoa | <1.00% | 0.30% |
Te Maama / Tikanga Tatauria | >99.0% (HPLC) | 99.7% |
1H NMR Spectrum | E rite ana ki te Hanganga | Ka tutuki |
Whakamutunga | Kua whakamatauria te hua me te whai ki nga whakaritenga kua tohua | |
Taupānga | Takawaenga o Gefitinib (CAS: 184475-35-2) |
Mōkī:Pounamu Fluorinated, Peeke pepa konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.
Tikanga Rokiroki:Kia kati te ipu ka penapena ki roto i te whare putunga hauhautanga, maroke (2~8 ℃) me te hau pai kia matara atu i nga matū hotokore.Tiaki i te marama me te makuku.
Tukunga:Tukuna ki te ao ma te rangi, ma te FedEx / DHL Express.Whakaratohia te tuku tere me te pono.
Me pehea te hoko?Whakapā maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 tau te wheako?Neke atu i te 15 tau o matou wheako ki te hanga me te kaweake i te whānuitanga o nga momo takawaenga rongoa kounga teitei, matū pai ranei.
Nga maakete matua?Hokona ki te maakete kaainga, Amerika Te Tai Tokerau, Uropi, Inia, Korea, Hapani, Ahitereiria, aha atu.
Nga painga?Ko te kounga teitei, te utu utu, nga ratonga ngaio me te tautoko hangarau, te tuku tere.
KoungaWhakapumautanga?Pūnaha whakahaere kounga tino.Ko nga taputapu ngaio mo te tātari ko te NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Tauira?Ko te nuinga o nga hua e whakarato ana i nga tauira kore utu mo te aromatawai kounga, me utu nga utu kaipuke e nga kaihoko.
Te arotake a wheketere?Nau mai te arotake wheketere.Whakaritea he hui i mua.
MOQ?Kaore he MOQ.Ka whakaaetia te ota iti.
Wā Tukunga? Mena kei roto i nga taonga, e toru nga ra ka whakamanahia te tuku.
Te kawe waka?Ma te Express (FedEx, DHL), ma te Air, ma te Moana.
Tuhinga?I muri i te ratonga hokohoko: COA, MOA, ROS, MSDS, me etahi atu ka taea te whakarato.
Whakaritenga Whakaritenga?Ka taea te whakarato ratonga whakahiato ritenga kia pai ai to hiahia rangahau.
Nga tikanga utu?Ko te nama Proforma ka tukuna tuatahi i muri i te whakapumautanga o te ota, ka kohia o maatau korero peeke.Te utu ma te T/T (Telex Transfer), PayPal, Western Union, etc.
7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-Kotahi (CAS: 199327-61-2) he takawaenga / poke o Gefitinib (CAS: 184475-35-2).Ko te Gefitinib he rongoa rongoa mo te mate pukupuku i hangaia e AstraZeneca, UK.Ko Gefitinib te raau taero tuatahi mo te rongoa mo te mate pukupuku pūtau kore-iti.Ka mahi ma te aukati i te huarahi whakawhiti tohu o te epidermal growth factor receptor tyrosine kinase (EGFR-TK).I te marama o Akuhata 2002, i hokohoko tuatahi a Gefitinib i Hapani hei rongoa tuatahi mo te mate pukupuku o te huhu kore-iti i raro i te ingoa hokohoko Iressa.I te marama o Haratua 2003, i whakaaetia e te US Food and Drug Administration a Gefitinib hei tuatoru-raina monotherapy mo nga turoro me te mate pukupuku o te huhu kore-iti kaore i te whai hua ki nga raau taero anticancer-a-platinum me te docetaxel chemotherapy.I tenei wa, kua whakaaetia a Gefitinib e Ahitereiria, Japan, Argentina, Singapore me Korea ki te Tonga mo te maimoatanga o te mate pukupuku mate pukupuku kore-iti.I te Hui-tanguru 28, 2005, i whakaaetia e te Whakahaere Kai me te Taauau o Haina a Gefitinib mo te maimoatanga o te mate pukupuku o te puku o te rohe, o te metastatic kore-iti ranei o te mate pukupuku o te puku (NSCLC) kua whiwhi i te chemotherapy i mua.I tenei wa kaore i te whakaaetia mo te whakamahi hei rongoa tuatahi mo te NSCLC matatau.I te Hūrae 1, 2009, i whakamanahia e te European Medicines Agency a Gefitinib mo te rarangi tuatahi, raina tuarua me te rarangi tuatoru o te maimoatanga o te mate pukupuku o te puku o te rohe, o te metastatic kore-iti ranei me nga ira ira EGFR i roto i nga pakeke.