Lapatinib Intermediate CAS 231278-84-5 Purity >98.0% (HPLC)
Ingoa matū | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Nga kupu taurite | Lapatinib Intermediate 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Tau CAS | 231278-84-5 |
Tūnga Taonga | I roto i te Stock, Production Tauine Up ki Taranata |
Tātai rāpoi | C26H17ClFN3O3 |
Taumaha rāpoi | 473.90 |
Te Whakarewa | 225.0 ki te 235.0 ℃ |
Kiato | 1.407±0.06 g/cm3 |
Taurangi Refactive | 1.694 |
COA & MSDS | Kei te waatea |
Taketake | Shanghai, Haina |
Waitohu | Ruifu Chemical |
Tūemi | Whakatakotoranga |
Te ahua | Kowhai Kowhai ki te Kowhai Paura Toka |
Te Maama / Tikanga Tatauria | >98.0% (HPLC) |
Te Whakarewa | 225.0~235.0℃ |
Ngaronga i te whakamaroke | <1.00% |
Te toenga i runga i te mura | <0.50% |
Nga poke katoa | <2.00% |
Konga Taamaha (hei Pb) | <20ppm |
Paerewa Whakamatau | Paerewa hinonga |
Whakamahinga | Takawaenga o API (CAS 388082-77-7) |
Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Kaata Drum, kia rite ranei ki te hiahia a te kaihoko
Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) he takawaenga o API (CAS 388082-77-7 ).(CAS 388082-77-7) he tarukino e aro ana ki te mate pukupuku uma i whakawhanakehia e British GlaxoSmithKline Co. Ko te aukati tyrosine kinase ka taea te aukati i te mahi tyrosine kinase o te tangata epidermal growth factor receptors 1 me 2 (ErbB1, ErbB2).Ka taea e ia te mahi motuhake i roto i nga momo huarahi, me te whakarite kia kore e taea e nga pūtau mate pukupuku uma te whiwhi tohu tipu.Ka aukati i nga waahi ATP intracellular EGFR (ErbB-1) me te HER2 (ErbB-2), te aukati i te phosphorylation pūtau puku me te whakahohe, te aukati i nga tohu-whakahaere na roto i te homogeneity me te heterogeneity o EGFR (ErbB-1) me HER2 (ErbB-1) whakaruruhau.