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Ibrutinib Intermediate CAS 330792-70-6 Purity >98.0% (HPLC) Atahanga Whakaatu
  • Ibrutinib Intermediate CAS 330792-70-6 Purity >98.0% (HPLC)

Ibrutinib Intermediate CAS 330792-70-6 Purity >98.0% (HPLC)

Whakaahuatanga Poto:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

CAS: 330792-70-6

Maamaa: >98.0% (HPLC)

Te ahua: Paura-White ki te Paura Kowhai Maama

Takawaenga o Ibrutinib (CAS: 936563-96-1) 

Whakapā: Takuta Alvin Huang

Pūkoro/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Nga takawaenga o Ibrutinib:

Ibrutinib CAS 936563-96-1
3-Hydroxypiperidine CAS 6859-99-0
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxybenzoic Waikawa CAS 2215-77-2
4-Phenoxyphenylboronic Acid CAS 51067-38-0
4-Aminopyrazolo [3,4-d] pyrimidine CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pirimidine CAS 151266-23-8
Ibrutinib Deacrylylpiperidine CAS 330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Nga Ahuatanga matū:

Ingoa matū 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Nga kupu taurite Ibrutinib Intermediate N-3;3-Amino-5-(4-Phenoxyphenyl)pyrazole-4-Carbonitrile;3-Amino-4-Cyano-5-(4-Phenoxyphenyl)pyrazole;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Tau CAS 330792-70-6
Tūnga Taonga I roto i te Stock, Production Tauine Up ki Taranata
Tātai rāpoi C16H12N4O
Taumaha rāpoi 276.29
Kiato 1.37±0.10 g/cm3
COA & MSDS Kei te waatea
Taketake Shanghai, Haina
Waitohu Ruifu Chemical

Whakatakotoranga:

Tūemi Whakatakotoranga
Te ahua Paura-White ki te Paura Kowhai Maama
Te Maama / Tikanga Tatauria >98.0% (HPLC)
Ngaronga i te whakamaroke <1.00%
Te toenga i runga i te mura <0.50%
Nga poke katoa <2.00%
Konga Taamaha (hei Pb) <20ppm
1 H NMR Spectrum E rite ana ki te Hanganga
Paerewa Whakamatau Paerewa hinonga
Whakamahinga Takawaenga o Ibrutinib (CAS: 936563-96-1)

Mōkī me te Rokiroki:

Mōkī: Pounamu, Peeke konumohe konumohe, 25kg / Cardboard Drum, kia rite ranei ki te hiahia a te kaihoko.

Tikanga Rokiroki:Whakaorangia i roto i nga ipu kua hiri ki te waahi makariri me te maroke;Tiaki i te marama me te makuku.

Painga:

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330792-70-6 - Taupānga:

Ko te 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) he takawaenga o Ibrutinib (CAS: 936563-96-1).Ko te Ibrutinib e whakaatu ana i te kaha aukati me te kore e taea te huri me te whiriwhiringa mo te mahi enzymatic Btk.I roto i te BCR ara-whakahohe DOHH2 raina pūtau, Ibrutinib inhibits autophosphorylation o Btk, phosphorylation o Btk's physiological substrate PLCγ, me te phosphorylation o atu kinase whakararo, ERK ki IC50 o 11 nM, 29 nM me 13 nM, aua.Ko te Ibrutinib e whakaatu ana i te nui o te whakaurunga o te cytotoxicity i roto i nga ruma lymphocytic leukemia (CLL).I tua atu, ko te Ibrutinib te akiaki i te mate o te pūtau i runga i te whakahohenga ara caspase me te whakahē i te kaha o nga pūtau CLL ki te whakatipu i muri i te tohu TLR.

Tuhia to korero ki konei ka tukuna mai ki a matou